S-100 beta chain Antibody (9A11B9): sc-81709
- S-100 β chain Antibody (9A11B9) is a mouse monoclonal IgG1 κ, cited in 4 publications, provided at 200 µg/ml
- raised against a recombinant protein corresponding to full length S-100 β chain of human origin
- recommended for detection of S-100 β chain of human origin by WB, IP, IF and IHC(P)
- See S-100 β chain (C-3): sc-393919 for S-100 β chain antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for S-100 β chain Antibody (9A11B9) for WB and IHC(P) applications. These reagents are now offered in bundles with S-100 β chain Antibody (9A11B9) (see ordering information below).
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S-100 β chain Antibody (9A11B9) is a mouse monoclonal IgG1 antibody that detects S-100 β chain in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). S-100 β chain plays a crucial role in various cellular processes, including the regulation of cell cycle progression and differentiation, which are vital for maintaining normal cellular function and tissue homeostasis. S-100 β chain is involved in the activation of calcium-induced calcium release, a mechanism essential for neurotransmitter release and neuronal signaling in the nervous system. S-100 β chain inhibits microtubule assembly and protein kinase C-mediated phosphorylation, further underscoring regulatory functions in cellular signaling pathways. S-100 β chain is primarily localized in the cytoplasm and nuclei of astrocytes, Schwann cells, and certain tumors, including ependymomas and astrogliomas, making S-100 β chain a significant marker in neurobiology and oncology. With diverse roles and widespread expression in various tissues, S-100 β chain serves as a valuable target for research and diagnostic applications, providing insights into both normal physiology and pathological conditions.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
S-100 beta chain Antibody (9A11B9) References:
- The current status of S-100B as a biomarker in melanoma. | Kruijff, S. and Hoekstra, HJ. 2012. Eur J Surg Oncol. 38: 281-5. PMID: 22240030
- S100B and schizophrenia. | Yelmo-Cruz, S., et al. 2013. Psychiatry Clin Neurosci. 67: 67-75. PMID: 23438158
- Timing Is Critical in Determining the Association Between Delirium and S100 Calcium-Binding Protein B. | Beishuizen, SJ., et al. 2015. J Am Geriatr Soc. 63: 2212-4. PMID: 26480996
- Cellular and molecular mechanisms of sarcopenia: the S100B perspective. | Riuzzi, F., et al. 2018. J Cachexia Sarcopenia Muscle. 9: 1255-1268. PMID: 30499235
- S100B in heart diseases. | Imbalzano, E., et al. 2020. Cardiovasc Pathol. 49: 107235. PMID: 32950202
- A model of full-length RAGE in complex with S100B. | Moysa, A., et al. 2021. Structure. 29: 989-1002.e6. PMID: 33887170
- S100B, Actor and Biomarker of Mild Traumatic Brain Injury. | Oris, C., et al. 2023. Int J Mol Sci. 24: PMID: 37047574
- The Role of Alarmins in Osteoarthritis Pathogenesis: HMGB1, S100B and IL-33. | Palumbo, A., et al. 2023. Int J Mol Sci. 24: PMID: 37569519
- Transcriptional repression of beige fat innervation via a YAP/TAZ-S100B axis. | Huang, X., et al. 2023. Nat Commun. 14: 7102. PMID: 37925548
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
S-100 β chain Antibody (9A11B9) | sc-81709 | 200 µg/ml | $322.00 | |||
S-100 β chain Antibody (9A11B9): m-IgG Fc BP-HRP Bundle | sc-539655 | 200 µg Ab; 10 µg BP | $361.00 | |||
S-100 β chain Antibody (9A11B9): m-IgG1 BP-HRP Bundle | sc-541637 | 200 µg Ab; 20 µg BP | $361.00 |