RXRα/β/γ Antibody (F-1): sc-46659

RXRα/β/γ Antibody (F-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects RXRα, RXRβ, and RXRγ in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). RXRα/β/γ (F-1) antibody is available in both non-conjugated and multiple conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates. The retinoid X receptor (RXR) family, which includes RXRα, RXRβ, and RXRγ, plays a crucial role in mediating the effects of retinoic acid, particularly 9-cis-retinoic acid, which is essential for various physiological processes. RXR receptors are primarily located in the nucleus, where they function as transcription factors that regulate gene expression in response to retinoid signaling. RXR receptors form heterodimers with other nuclear receptors, such as retinoic acid receptors (RARs), thyroid hormone receptors, and vitamin D3 receptors, thereby enhancing the specificity and diversity of retinoid signaling pathways. RXR interaction with these other receptors is vital for processes such as cellular differentiation, development, and metabolism, making RXRs important targets for research in developmental biology and therapeutic interventions.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-RXRα/β/γ Antibody (F-1) has 38 citations in a variety of scientific publications.

Primary antibodies like Anti-RXRα/β/γ Antibody (F-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

RXRα/β/γ Antibody (F-1) Specifications

Alternate Product Name: RXRα/β/γ

Product Clone Name: F-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 198-462

Epitope Target: RXRα

Epitope Species: human

Product Reactivity/Detection: RXRα, RXRβ and RXRγ

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 38 citations in various scientific publications

Available Conjugates/Forms for RXRα/β/γ Antibody (F-1): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin, X: TransCruz Reagent