RUNDC3A Antibody (E-2): sc-377090

RUNDC3A Antibody (E-2) is a mouse monoclonal IgG1 antibody that detects RUNDC3A in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). RUNDC3A, also known as RPIP-8 or RAP2IP, is a 446 amino acid protein that functions as an effector of RAP2A, particularly in neuronal cells, playing a crucial role in cellular signaling pathways. RUNDC3A is predominantly expressed in the testis, brain, kidney, and liver, and is encoded by a gene located on human chromosome 17q21.31, a region that is significant due to its association with key tumor suppressor genes such as p53 and BRCA1. RUNDC3A presence in these tissues suggests involvement in critical physiological processes, including neuronal function and development. Additionally, RUNDC3A undergoes alternative splicing to produce four isoforms, which may have distinct functional roles or regulatory mechanisms, further emphasizing the importance of studying RUNDC3A in the context of cellular health and disease. Anti-RUNDC3A antibody (E-2) is an essential tool for researchers aiming to explore the intricate functions of RUNDC3A and its implications in various biological processes and disease states.

The preferred RUNDC3A antibody is RUNDC3A Antibody (H-9): sc-390248.