RT1-D Antibody (OX17): sc-53075
- RT1-D Antibody (OX17) is a mouse monoclonal IgG1 κ RT1-D antibody, cited in 2 publications, provided at 200 µg/ml
- raised against MHC Class II RT1D of rat origin
- RT1-D Antibody (OX17) is recommended for detection of RT1-D of mouse and rat origin by WB, IP, IF and FCM
- Anti-RT1-D Antibody (OX17) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for RT1-D Antibody (OX17) for WB applications. These reagents are now offered in bundles with RT1-D Antibody (OX17) (see ordering information below).
RT1-D Antibody (OX17) is a mouse monoclonal IgG1 kappa light chain antibody that detects RT1-D protein of mouse and rat origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). RT1-D (OX17) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. RT1-D protein is a major histocompatibility complex (MHC) class II antigen, which plays a crucial role in the immune system by presenting processed antigens to CD4+ helper T-cells, thereby initiating and regulating immune responses. The structure of RT1-D consists of an alpha and beta chain that form a heterodimer, allowing binding to peptide fragments derived from extracellular proteins. This structural configuration ensures T-cells can recognize and respond to pathogens, thus maintaining immune surveillance and homeostasis. The ability of RT1-D to interact with various peptides and polymorphic nature contribute to the diversity of immune responses, making RT1-D a vital component in the adaptive immune system.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
RT1-D Antibody (OX17) References:
- HLA-DMA and HLA-DMB alleles in German patients with type 1 diabetes mellitus. | Siegmund, T., et al. 1999. Tissue Antigens. 54: 291-4. PMID: 10519369
- The association of HLA-DM genes with rheumatoid arthritis in Eastern France. | Toussirot, E., et al. 2000. Hum Immunol. 61: 303-8. PMID: 10689120
- Functional HLA-DM on the surface of B cells and immature dendritic cells. | Arndt, SO., et al. 2000. EMBO J. 19: 1241-51. PMID: 10716924
- Functional characterization of a lysosomal sorting motif in the cytoplasmic tail of HLA-DObeta. | Brunet, A., et al. 2000. J Biol Chem. 275: 37062-71. PMID: 10964920
- The down-regulation of HLA-DM gene expression in rheumatoid arthritis is not related to their promoter polymorphism. | Louis-Plence, P., et al. 2000. J Immunol. 165: 4861-9. PMID: 11046010
- Determination of the HLA-DM interaction site on HLA-DR molecules. | Doebele, RC., et al. 2000. Immunity. 13: 517-27. PMID: 11070170
- Differential splenic migration of dendritic cells after immunologic unresponsiveness in rat hepatic allografts induced by pretransplant donor-specific transfusion. | Ohshiro, H., et al. 2001. J Surg Res. 101: 29-36. PMID: 11676551
- Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus. | Fukumoto, T., et al. 1982. Eur J Immunol. 12: 237-43. PMID: 6178598
- A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules. | Kropshofer, H., et al. 1998. EMBO J. 17: 2971-81. PMID: 9606180
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RT1-D Antibody (OX17) | sc-53075 | 200 µg/ml | $322.00 | |||
RT1-D Antibody (OX17): m-IgG Fc BP-HRP Bundle | sc-526764 | 200 µg Ab; 10 µg BP | $361.00 | |||
RT1-D Antibody (OX17): m-IgG1 BP-HRP Bundle | sc-532137 | 200 µg Ab; 20 µg BP | $361.00 | |||
RT1-D Antibody (OX17) AC | sc-53075 AC | 500 µg/ml, 25% agarose | $424.00 | |||
RT1-D Antibody (OX17) HRP | sc-53075 HRP | 200 µg/ml | $322.00 | |||
RT1-D Antibody (OX17) FITC | sc-53075 FITC | 200 µg/ml | $336.00 | |||
RT1-D Antibody (OX17) PE | sc-53075 PE | 200 µg/ml | $349.00 | |||
RT1-D Antibody (OX17) Alexa Fluor® 488 | sc-53075 AF488 | 200 µg/ml | $364.00 | |||
RT1-D Antibody (OX17) Alexa Fluor® 546 | sc-53075 AF546 | 200 µg/ml | $364.00 | |||
RT1-D Antibody (OX17) Alexa Fluor® 594 | sc-53075 AF594 | 200 µg/ml | $364.00 | |||
RT1-D Antibody (OX17) Alexa Fluor® 647 | sc-53075 AF647 | 200 µg/ml | $364.00 | |||
RT1-D Antibody (OX17) Alexa Fluor® 680 | sc-53075 AF680 | 200 µg/ml | $364.00 | |||
RT1-D Antibody (OX17) Alexa Fluor® 790 | sc-53075 AF790 | 200 µg/ml | $364.00 |