RRS1 Antibody (B-7): sc-393746

RRS1 Antibody (B-7) is a mouse monoclonal IgG1 antibody that detects RRS1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RRS1, also known as KIAA0112, is a 365 amino acid protein that plays a crucial role in ribosome biogenesis and chromosome congression, highlighting its importance in cellular function and division. RRS1 is primarily localized in the nucleolus, where RRS1 is essential for the proper assembly of ribosomal subunits, a process vital for protein synthesis. Disruption of RRS1 function can lead to significant cellular consequences, including mitotic delays due to abnormal spindle organization and chromosome alignment, which can ultimately affect cell proliferation and contribute to various diseases. The gene encoding RRS1 is located on human chromosome 8q13.1, a region associated with numerous genetic disorders and malignancies, including schizophrenia and certain leukemias. Anti-RRS1 antibody (B-7) is an invaluable tool for researchers studying ribosome biogenesis and its implications in cellular health and disease.

The preferred RRS1 antibody is RRS1 Antibody (H-5): sc-515462.