
RRP9 Antibody (RS-9) is a mouse monoclonal IgG2b antibody that detects RRP9 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). RRP9, also known as ribosomal RNA processing 9 or small subunit processome component, is a crucial 475 amino acid nucleolar protein that plays a significant role in the modification and processing of precursor ribosomal RNA (rRNA). RRP9 is a key component of small nucleolar ribonucleoprotein particles (snoRNPs) and is specifically involved in the interaction with the U3 snoRNA complex, binding to a fragment known as 3UBC, which contains a box B/C motif. The functionality of RRP9 is contingent upon the binding of the snRNP protein NHPX to the B/C motif and the presence of a conserved tertiary structure that flanks this motif, which together facilitate RRP9′s participation in pre-rRNA processing. Notably, RRP9′s seven WD repeats are essential for its localization within the nucleolus and its ability to bind U3 snoRNA, underscoring the importance of its structural integrity in ribosome biogenesis. Anti-RRP9 antibody (RS-9) is an invaluable tool for researchers studying ribosomal RNA processing and the intricate mechanisms of nucleolar function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RRP9 Antibody (RS-9) | sc-100592 | 50 µg/0.5 ml | $322.00 |