Date published: 2025-11-23

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RPS6KL1 Antibody (273CT4.5.3): sc-517359

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Datasheets
  • RPS6KL1 Antibody (273CT4.5.3) is a mouse monoclonal IgM RPS6KL1 antibody provided at 100 µg/ml
  • raised against a recombinant protein corresponding to RPS6KL1 of human origin
  • recommended for detection of RPS6KL1 of mouse, rat and human origin by WB
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for RPS6KL1 Antibody (273CT4.5.3). This work is in progress.

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    RPS6KL1 Antibody (273CT4.5.3) is a mouse monoclonal IgM antibody that detects RPS6KL1 of mouse, rat, and human origin by western blotting (WB). Anti-RPS6KL1 antibody (273CT4.5.3) is available as a non-conjugated format. RPS6KL1, also known as ribosomal protein S6 kinase-like 1, is a 549 amino acid protein that plays a crucial role in cellular signaling pathways, particularly those involved in cell growth and proliferation. RPS6KL1 belongs to the Ser/Thr protein kinase family, specifically the S6 kinase subfamily, and features one MIT domain and a protein kinase domain. RPS6KL1 helps regulate ribosomal biogenesis and protein synthesis, which are essential processes for maintaining cellular function and responding to growth signals. RPS6KL1 is encoded on human chromosome 14, a region associated with various genetic disorders, including Alzheimer′s disease and α1-antitrypsin deficiency. RPS6KL1 and its regulatory functions are vital for understanding cell growth mechanisms and potential disease implications.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    RPS6KL1 Antibody (273CT4.5.3) References:

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    3. A germline-specific class of small RNAs binds mammalian Piwi proteins.  |  Girard, A., et al. 2006. Nature. 442: 199-202. PMID: 16751776
    4. The genetics of very early onset Alzheimer disease.  |  Filley, CM., et al. 2007. Cogn Behav Neurol. 20: 149-56. PMID: 17846513
    5. A polymorphism of the alpha1-antitrypsin gene represents a risk factor for liver disease.  |  Chappell, S., et al. 2008. Hepatology. 47: 127-32. PMID: 17972336
    6. Genotype-phenotype relationships of presenilin-1 mutations in Alzheimer's disease: an update.  |  Larner, AJ. and Doran, M. 2009. J Alzheimers Dis. 17: 259-65. PMID: 19221408
    7. Alpha-1-antitrypsin phenotypes in adult liver disease patients.  |  Topic, A., et al. 2009. Ups J Med Sci. 114: 228-34. PMID: 19961268
    8. Identification of candidate oncogenes in human colorectal cancers with microsatellite instability.  |  Gylfe, AE., et al. 2013. Gastroenterology. 145: 540-3.e22. PMID: 23684749
    9. Rare Copy Number Variants in Array-Based Comparative Genomic Hybridization in Early-Onset Skeletal Fragility.  |  Costantini, A., et al. 2018. Front Endocrinol (Lausanne). 9: 380. PMID: 30042735
    10. The plasma peptides of sepsis.  |  Thavarajah, T., et al. 2020. Clin Proteomics. 17: 26. PMID: 32636717
    11. Comprehensive analysis of ECHDC3 as a potential biomarker and therapeutic target for acute myeloid leukemia: Bioinformatic analysis and experimental verification.  |  Zhao, Y., et al. 2022. Front Oncol. 12: 947492. PMID: 36172164
    12. Identification of Distinct Genetic Profiles of Palindromic Rheumatism Using Whole-Exome Sequencing.  |  Zheng, C., et al. 2023. Arthritis Rheumatol. 75: 1947-1957. PMID: 37219934

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    RPS6KL1 Antibody (273CT4.5.3)

    sc-517359
    100 µg/ml
    $316.00