Rotavirus capsid Antibody (0581): sc-69945
- Rotavirus capsid Antibody (0581) is a mouse monoclonal IgG2b provided at 100 µg/ml
- raised against Rotavirus capsid
- recommended for detection of intact RRV, WA and bovine strains of Rotavirus origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Rotavirus capsid Antibody (0581). This work is in progress.
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Rotavirus capsid Antibody (0581) is a mouse monoclonal IgG2b antibody that detects Rotavirus, with species reactivity specific to Rotavirus, and is suitable for enzyme-linked immunosorbent assay (ELISA). Anti-Rotavirus capsid antibody (0581) plays a crucial role in studying rotavirus infections, which are a leading cause of severe gastroenteritis in infants and young children. The rotavirus capsid is composed of three concentric protein layers, with the outer layers, VP4 and VP7, being essential for viral entry into host cells. These proteins facilitate virus attachment to cell membranes and undergo calcium-dependent conformational changes critical for viral entry. Understanding rotavirus capsid structure provides insights into host cell interactions and can inform targeted therapy and vaccine development. Rotavirus capsid monoclonal antibody (0581) enables effective investigation of rotavirus pathogenesis mechanisms and contributes to advancing prevention and treatment strategies for rotavirus infections.
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Rotavirus capsid Antibody (0581) References:
- VP4 differentially regulates TRAF2 signaling, disengaging JNK activation while directing NF-kappa B to effect rotavirus-specific cellular responses. | LaMonica, R., et al. 2001. J Biol Chem. 276: 19889-96. PMID: 11262403
- Rotavirus virus-like particles as surrogates in environmental persistence and inactivation studies. | Caballero, S., et al. 2004. Appl Environ Microbiol. 70: 3904-9. PMID: 15240262
- Detection and characterization of human group C rotavirus in the pediatric population of Barcelona, Spain. | Abid, I., et al. 2007. J Clin Virol. 38: 78-82. PMID: 17070729
- Geometric mismatches within the concentric layers of rotavirus particles: a potential regulatory switch of viral particle transcription activity. | Libersou, S., et al. 2008. J Virol. 82: 2844-52. PMID: 18184711
- Self-assembled virus-like particles from rotavirus structural protein VP6 for targeted drug delivery. | Zhao, Q., et al. 2011. Bioconjug Chem. 22: 346-52. PMID: 21338097
- Regulation of rotavirus polymerase activity by inner capsid proteins. | Gridley, CL. and Patton, JT. 2014. Curr Opin Virol. 9: 31-8. PMID: 25243800
- Sequence analysis and structural implications of rotavirus capsid proteins. | Parbhoo, N., et al. 2016. Acta Virol. 60: 260-70. PMID: 27640436
- Cranberry and Grape Juices Affect Tight Junction Function and Structural Integrity of Rotavirus-Infected Monkey Kidney Epithelial Cell Monolayers. | Lipson, SM., et al. 2011. Food Environ Virol. 3: 46-54. PMID: 35255646
- Specific binding sites on Rhesus rotavirus capsid protein dictate the method of endocytosis inducing the murine model of biliary atresia. | Temple, H., et al. 2024. Am J Physiol Gastrointest Liver Physiol. 327: G267-G283. PMID: 38860860
- Assembly of double-layered virus-like particles in mammalian cells by coexpression of human rotavirus VP2 and VP6. | González, SA. and Affranchino, JL. 1995. J Gen Virol. 76 (Pt 9): 2357-60. PMID: 7561777
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rotavirus capsid Antibody (0581) | sc-69945 | 100 µg/ml | $316.00 |