Rotavirus capsid Antibody (0531): sc-69943
- Rotavirus capsid Antibody (0531) is a mouse monoclonal IgG2b provided at 100 µg/ml
- raised against Rotavirus capsid
- recommended for detection of intact RRV, WA and bovine strains of Rotavirus origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Rotavirus capsid Antibody (0531). This work is in progress.
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Rotavirus capsid Antibody (0531) is a mouse monoclonal IgG2b antibody that detects Rotavirus protein by enzyme-linked immunosorbent assay (ELISA). Anti-Rotavirus capsid antibody (0531) plays a crucial role in understanding the structure of the Rotavirus capsid, which is composed of three concentric protein layers essential for viral infection of host cells. The outer layers, VP4 and VP7, facilitate viral entry into host cells through direct membrane penetration or endocytosis. This structural arrangement protects viral RNA while aiding stability and infectivity, making Rotavirus capsid (0531) antibody valuable for therapeutic interventions and vaccine development. Rotavirus capsid monoclonal antibody (0531) enables researchers to gain insights into infection mechanisms and develop effective treatments against this leading cause of gastroenteritis in infants and young children.
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Rotavirus capsid Antibody (0531) References:
- Rotavirus capsid protein VP5* permeabilizes membranes. | Denisova, E., et al. 1999. J Virol. 73: 3147-53. PMID: 10074166
- Antibodies to rotavirus outer capsid glycoprotein VP7 neutralize infectivity by inhibiting virion decapsidation. | Ludert, JE., et al. 2002. J Virol. 76: 6643-51. PMID: 12050377
- Trypsin is associated with the rotavirus capsid and is activated by solubilization of outer capsid proteins. | Benureau, Y., et al. 2005. J Gen Virol. 86: 3143-3151. PMID: 16227238
- Immunogenicity and virus-like particle formation of rotavirus capsid proteins produced in transgenic plants. | Yang, Y., et al. 2011. Sci China Life Sci. 54: 82-9. PMID: 21104033
- Regulation of rotavirus polymerase activity by inner capsid proteins. | Gridley, CL. and Patton, JT. 2014. Curr Opin Virol. 9: 31-8. PMID: 25243800
- Rotavirus capsid VP6 protein acts as an adjuvant in vivo for norovirus virus-like particles in a combination vaccine. | Blazevic, V., et al. 2016. Hum Vaccin Immunother. 12: 740-8. PMID: 26467630
- Sequence analysis and structural implications of rotavirus capsid proteins. | Parbhoo, N., et al. 2016. Acta Virol. 60: 260-70. PMID: 27640436
- Rotavirus capsid VP6 tubular and spherical nanostructures act as local adjuvants when co-delivered with norovirus VLPs. | Malm, M., et al. 2017. Clin Exp Immunol. 189: 331-341. PMID: 28407442
- Evaluation of the immunogenicity of auxotrophic Lactobacillus with CRISPR-Cas9D10A system-mediated chromosomal editing to express porcine rotavirus capsid protein VP4. | Li, F., et al. 2022. Virulence. 13: 1315-1330. PMID: 35920261
- Specific binding sites on Rhesus rotavirus capsid protein dictate the method of endocytosis inducing the murine model of biliary atresia. | Temple, H., et al. 2024. Am J Physiol Gastrointest Liver Physiol. 327: G267-G283. PMID: 38860860
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rotavirus capsid Antibody (0531) | sc-69943 | 100 µg/ml | $316.00 |