Molecular structure of Ro 64-5229, CAS Number: 246852-46-0
Ro 64-5229 (CAS 246852-46-0)
Application:
Ro 64-5229 is a selective, non-competitive mGluR-2 antagonist
CAS Number:
246852-46-0
Molecular Weight:
352.26
Molecular Formula:
C17H19Cl2N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ro 64-5229 is a selective, non-competitive mGlu2 antagonist that has been shown to inhibit GTPγ35S binding to mGlu2-containing membranes with an IC50of ~ 0.11 µM.
Ro 64-5229 (CAS 246852-46-0) References
Kolczewski et al (1999) Synthesis of heterocyclic enol ethers and their use as a group 2 metabotropic glutamate receptor antagonists. Bioorg.Med.Chem.Lett. 9 2173. Brauner-Osbourne et al (2007) Structure, pharmacology and therapeutic prospects of family CInhibitor of:
mGluR-2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ro 64-5229, 10 mg | sc-361308 | 10 mg | $350.00 | |||
Ro 64-5229, 50 mg | sc-361308A | 50 mg | $1575.00 |