Anti-RNGTT Antibody (D-3) is a mouse monoclonal IgG1 (kappa light chain) RNGTT antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 57-89 near the N-terminus of RNGTT of human origin
Anti-RNGTT Antibody (D-3) is recommended for detection of RNGTT of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and bovine
Anti-RNGTT Antibody (D-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of RNGTT (D-3): sc-377464.
m-IgGκ BP-HRP is the preferred secondary detection reagent for RNGTT Antibody (D-3) for WB applications. This reagent is now offered in a bundle with RNGTT Antibody (D-3) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
RNGTT Antibody (D-3) is a high quality monoclonal RNGTT antibody (also designated RNGTT antibody) suitable for the detection of the RNGTT protein of mouse, rat and human origin. RNGTT Antibody (D-3) is available as both the non-conjugated anti-RNGTT antibody form, as well as multiple conjugated forms of anti-RNGTT antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. RNGTT (RNA guanylyltransferase and 5′-phosphatase), also known as HCE, HCE1, hCAP or CAP1A, is a 597 amino acid protein that localizes to the nucleus and exists as four alternatively spliced isoforms. Expressed in kidney, lung, heart, brain, liver, testis, skin and muscle, RNGTT acts as a bifunctional mRNA-capping enzyme that exhibits RNA 5′-triphosphatase activity at its N-terminus and mRNA guanylyltransferase activity at its C-terminus. Via its catalytic activity, RNGTT facilitates the first two steps of mRNA cap formation, naming the removal of a gamma-phosphate from the end of nascent mRNA and the subsequent transfer of the phospho residue to the 5′-diphosphate terminus. The gene encoding RNGTT maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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