Molecular structure of RN 1734, CAS Number: 946387-07-1
RN 1734 (CAS 946387-07-1)
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Alternate Names:
2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
Application:
RN 1734 is a selective TRPV4 antagonist
CAS Number:
946387-07-1
Purity:
≥94%
Molecular Weight:
353.31
Molecular Formula:
C14H22Cl2N2O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
RN 1734 is a selective TRPV4 antagonist (IC50 values are 2.3, 5.9 and 3.2 μM for hTRPV4, mTRPV4 and rTRPV4 receptors respectively). RN 1734 has been shown to display selectivity for TRPV4 over other TRP channels (IC50 values are 2.3, >30, >30 and >100 μM for TRPV4, TRPV3, TRPM8 and TRPV1 respectively).
RN 1734 (CAS 946387-07-1) References
Vincent et al (2009) Identification and characterization of novel TRPV4 modulators. Biochem.Biophys.Res.Comms. 389 490.Inhibitor of:
TRPV, and TRPV4.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RN 1734, 10 mg | sc-296273 | 10 mg | $128.00 | |||
RN 1734, 50 mg | sc-296273A | 50 mg | $500.00 |