RIP4 Antibody (387.1): sc-100428
- RIP4 Antibody (387.1) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against recombinant RIP4 of human origin
- recommended for detection of RIP4 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for RIP4 Antibody (387.1). This work is in progress.
QUICK LINKS
RIP4 Antibody (387.1) is a mouse monoclonal IgG1 antibody that detects RIP4 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). RIP4, also known as receptor-interacting serine/threonine-protein kinase 4, plays a crucial role in cellular signaling pathways, particularly in the modulation of epidermal growth and differentiation. RIP4 is primarily located in the cytoplasm and is associated with the plasma membrane, where RIP4 interacts with tumor necrosis factor receptors (TNFRs) to facilitate downstream signaling events that lead to apoptosis and the activation of nuclear factor kappa B (NFκB). The presence of ten ankyrin repeats and a protein kinase domain in RIP4′s structure is significant, as these features are essential for interaction with various signaling molecules and for kinase activity, which is vital for regulating cellular responses to external stimuli. Additionally, RIP4 exists in two isoforms due to alternative splicing, which may contribute to functional diversity in different cellular contexts. RIP4 (387.1) monoclonal antibody is an invaluable tool for researchers studying the intricate mechanisms of cell signaling and the role of RIP4 in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RIP4 Antibody (387.1) | sc-100428 | 100 µg/ml | $339.00 |