Ricin A Antibody (RA999): sc-52190
- Ricin A Antibody (RA999) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against full length Ricinus communis agglutinin
- recommended for detection of RCA120 and the A chain of RCA60 of Ricinus communis origin by WB and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Ricin A Antibody (RA999). This work is in progress.
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Ricin A Antibody (RA999) is a mouse monoclonal IgG1 antibody that detects Ricin A from Ricinus communis by western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). Ricin A, also known as the A chain of ricin toxin, plays a critical role in the toxin′s mechanism of action by inhibiting protein synthesis through RNA N-glycosidase activity. This enzymatic function targets the 28S rRNA of the 60S ribosomal subunit, specifically depurinating adenine 4324, which ultimately halts protein biosynthesis in affected cells. The ability of Ricin A to disrupt cellular function makes Ricin A a potent toxin, and understanding Ricin A structure is essential for developing therapeutic strategies and countermeasures against ricin exposure. The crystal structure of Ricin A has been elucidated, revealing the intricate arrangement of domains, which is crucial for binding and enzymatic activity. Anti-Ricin A antibody (RA999) serves as an invaluable tool for researchers studying biochemical pathways affected by ricin and for developing assays to detect this potent toxin in various samples.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ricin A Antibody (RA999) | sc-52190 | 100 µg/ml | $316.00 |