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Ricin A Antibody (RA519) is a mouse monoclonal IgG1 antibody that detects Ricin A from Ricinus communis by western blotting (WB). Ricin A, also known as the A chain of ricin toxin, plays a critical role in protein synthesis inhibition through RNA N-glycosidase enzymatic activity. This function enables Ricin A to depurinate adenine 4324 in the 28S rRNA of the 60S ribosomal subunit, effectively halting protein biosynthesis and leading to cell death. The unique configuration of Ricin A facilitates interaction with ribosomal RNA, enhancing toxic effects. Anti-Ricin A antibody (RA519) serves as an invaluable tool for researchers investigating molecular mechanisms of ricin toxicity and developing countermeasures against this dangerous toxin.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ricin A Antibody (RA519) | sc-52189 | 100 µg/ml | $322.00 |