Ricin A Antibody (CP23): sc-52184
- Ricin A Antibody (CP23) is a mouse monoclonal IgM provided at 100 µg/ml
- raised against purified Ricinus communis agglutinin
- recommended for detection of the A chain of RCA60R and RCA120 of Ricinus communis origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Ricin A Antibody (CP23). This work is in progress.
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Ricin A Antibody (CP23) is a mouse monoclonal IgM antibody that detects Ricin A from Ricinus communis by enzyme-linked immunosorbent assay (ELISA). Ricin A, also known as the A chain of ricin toxin, plays a critical role in protein biosynthesis inhibition through RNA N-glycosidase activity, specifically depurinating adenine 4324 in the 28S rRNA of the 60S ribosomal subunit, leading to disrupted ribosomal function and cell death. Ricin A consists of two distinct domains: a lectin domain facilitating cell surface receptor binding and a catalytic domain exerting toxic effects. This precise domain arrangement enables effective A chain entry into target cells following B chain binding. Ricin A′s protein synthesis inhibition capability makes anti-Ricin A antibody (CP23) an invaluable tool for investigating biochemical pathways affected by this toxin and developing detection assays.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ricin A Antibody (CP23) | sc-52184 | 100 µg/ml | $316.00 |