Ribosomal Protein L4 Antibody (RQ-7): sc-100838

Ribosomal Protein L4 Antibody (RQ-7) is a mouse monoclonal IgG2a kappa light chain antibody that detects Ribosomal Protein L4 (RPL4) in mouse, rat, and human samples by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-RPL4 antibody (RQ-7) is available as a non-conjugated format. RPL4, also known as RPL1, is a crucial component of the large 60S ribosomal subunit, consisting of 427 amino acids and playing a vital role in protein synthesis. RPL4 (RQ-7) antibody recognizes RPL4 in the cytoplasm, where RPL4 contributes to ribosome assembly and function, translating messenger RNA into proteins. Proper RPL4 localization is essential for efficient ribosome biogenesis and function, as disruption can lead to impaired protein synthesis and cellular stress. RPL4 interacts with RNA helicase II (DDX21), a multifunctional nucleolar protein involved in ribosomal RNA processing, highlighting RPL4′s importance in maintaining ribosomal integrity and function. Anti-RPL4 antibody (RQ-7) serves as an invaluable tool for researchers studying ribosome biology and cellular processes across multiple species and applications.

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Ribosomal Protein L4 Antibody (RQ-7) References:

1. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.  |  Yoshihama, M., et al. 2002. Genome Res. 12: 379-90. PMID: 11875025
2. Expression of ribosomal protein L4 (rpL4) during neurogenesis and 5-azacytidine (5AzC)-induced apoptotic process in the rat.  |  Ueno, M., et al. 2002. Histol Histopathol. 17: 789-98. PMID: 12168788
3. Functional interaction between RNA helicase II/Gu(alpha) and ribosomal protein L4.  |  Yang, H., et al. 2005. FEBS J. 272: 3788-802. PMID: 16045751
4. Human ribosomal protein L4: cloning and sequencing of the cDNA and primary structure of the protein.  |  Bagni, C., et al. 1993. Biochim Biophys Acta. 1216: 475-8. PMID: 8268230
5. The nuclear RPL4 gene encodes a chloroplast protein that co-purifies with the T7-like transcription complex as well as plastid ribosomes.  |  Trifa, Y., et al. 1998. J Biol Chem. 273: 3980-5. PMID: 9461586
6. A map of 75 human ribosomal protein genes.  |  Kenmochi, N., et al. 1998. Genome Res. 8: 509-23. PMID: 9582194
7. Increased expression of rat ribosomal protein L4 mRNA in 5-azacytidine-treated PC12 cells prior to apoptosis.  |  Kajikawa, S., et al. 1998. Biochem Biophys Res Commun. 252: 220-4. PMID: 9813173

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Ribosomal Protein L4 Antibody (RQ-7) has 15 citations in a variety of scientific publications.

Primary antibodies like Anti-Ribosomal Protein L4 Antibody (RQ-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Ribosomal Protein L4 Antibody (RQ-7) Specifications

Alternate Product Name: Ribosomal Protein L4

Product Clone Name: RQ-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 251-351

Epitope Target: Ribosomal Protein L4

Epitope Species: human

Product Reactivity/Detection: Ribosomal Protein L4

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 15 citations in various scientific publications

Available Conjugates/Forms for Ribosomal Protein L4 Antibody (RQ-7): N/A