RGS9-1 Antibody (D3): sc-53988

RGS9-1 Antibody (D3) is a mouse monoclonal IgG1 antibody that detects RGS9-1 in mouse, rat, and bovine samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RGS9-1 is a crucial isoform of the RGS9 protein family, primarily located in the photoreceptor cells of the retina, where RGS9-1 plays a vital role in the visual signaling pathway. RGS9-1 is essential for the rapid recovery of the light response, allowing photoreceptors to adapt quickly to changes in light intensity. RGS9-1 is tightly bound to the disk membranes of these cells, and RGS9-1′s interaction with R9AP anchors RGS9-1 effectively, ensuring proper localization and function. Notably, RGS9-1 undergoes phosphorylation by protein kinase A, a modification that enhances RGS9-1′s activity and contributes to a stronger photoresponse in dark-adapted cells, thereby playing a significant role in visual sensitivity and adaptation. Anti-RGS9-1 antibody (D3) is an invaluable tool for researchers studying the dynamics of visual signaling and the underlying mechanisms of phototransduction in various species.

The preferred RGS9 antibody is RGS9 Antibody (C-8): sc-377252.