Anti-Rev-erbβ Antibody (D-8) is a mouse monoclonal IgG1 (kappa light chain) Rev-erbβ antibody provided at 200 µg/ml
raised against amino acids 195-267 mapping within an internal region of Rev-erbβ of mouse origin
Anti-Rev-erb beta Antibody (D-8) is recommended for detection of Rev-erbβ of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-Rev-erb beta Antibody (D-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for ChIP application (sc-398252 X, 200 µg/0.1 ml)
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Rev-erbβ (D-8): sc-398252.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Rev-erbβ Antibody (D-8) is a high quality monoclonal Rev-erb beta antibody (also designated Rev-erbβ antibody) suitable for the detection of the Rev-erb beta protein of mouse, rat and human origin. Rev-erbβ Antibody (D-8) is available as both the non-conjugated anti-Rev-erb beta antibody form, as well as multiple conjugated forms of anti-Rev-erb beta antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Orphan nuclear receptors NR1D1 and NR1D2 are more commonly designated Rev-erbα and Rev-erbβ, respectively. Rev-erbα acts as a receptor for triiodothyronine and is composed of three domains: a modulating N-terminal domain, a C-terminal steroid binding domain and a DNA-binding domain. Rev-erbβ binds to the sequences 5′-AATGTAGGTCA-3′ and 5′-ATAACTAGGTCA-3′ and acts as a competitive repressor of RORα function. It interacts with NCOA5 co-activator which leads to an increase in transcription. Both Rev-erbα and Rev-erbβ are nuclear proteins belonging to the nuclear hormone receptor family of proteins.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Rated 5 out of
Danyi Lu from
good featuresWestern blot results showed that this antibody specially reacted with mouse Nr1d2 but not mouse Nr1d1 protein.
Date published: 2017-01-14
Rated 5 out of
detect a strong band in mouse Nr1d2 transfecteddetect a strong band in mouse Nr1d2 transfected HEK293 whole cell lysate, with weak bands in non-transfected or mouse Nr1d1-transfected lysates
Date published: 2016-08-30
Rated 5 out of
Very good Western blot data of RevVery good Western blot data of Rev-erb expression in HeLa nuclear extract and EOC 20 whole cell lysate . -SCBT QC
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn