REEP4 Antibody (H-12): sc-398191
- REEP4 Antibody (H-12) is a mouse monoclonal IgG2a κ REEP4 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 174-207 within an internal region of REEP4 of human origin
- REEP4 Antibody (H-12) is recommended for detection of REEP4 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-REEP4 Antibody (H-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for REEP4 Antibody (H-12) for WB applications. These reagents are now offered in bundles with REEP4 Antibody (H-12) (see ordering information below).
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REEP4 Antibody (H-12) is a mouse monoclonal IgG2a kappa light chain antibody that detects REEP4 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). REEP4 (H-12) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. REEP4 protein, also known as receptor expression-enhancing protein 4, plays a crucial role in trafficking and expression of odorant receptors on the cell surface, which is vital for proper functioning of the olfactory system. Although REEP4 is not expressed in olfactory neurons, REEP4′s interaction with odorant receptor proteins suggests that REEP4 may enhance receptor availability, thereby influencing sensitivity and specificity of odor detection. REEP4 is a member of the DP1 family and exists in two isoforms due to alternative splicing events. The gene encoding REEP4 is located on human chromosome 8p21.3, a region associated with various diseases, including schizophrenia, bipolar disorder, and certain types of cancer, highlighting the importance of understanding REEP4′s functional dynamics in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
REEP4 Antibody (H-12) References:
- Chromosomes 8 and 10 workshop. | Wildenauer, DB. and Schwab, SG. 1999. Am J Med Genet. 88: 239-43. PMID: 10374738
- Preferential expression of an intact WRN gene in Werner syndrome cell lines in which a normal chromosome 8 has been introduced. | Kashino, G., et al. 2001. Biochem Biophys Res Commun. 289: 111-5. PMID: 11708785
- Cytogenetic mapping of a novel locus for type II Waardenburg syndrome. | Selicorni, A., et al. 2002. Hum Genet. 110: 64-7. PMID: 11810298
- RTP family members induce functional expression of mammalian odorant receptors. | Saito, H., et al. 2004. Cell. 119: 679-91. PMID: 15550249
- Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. | McQueen, MB., et al. 2005. Am J Hum Genet. 77: 582-95. PMID: 16175504
- DNA sequence and analysis of human chromosome 8. | Nusbaum, C., et al. 2006. Nature. 439: 331-5. PMID: 16421571
- Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. | Agrelo, R., et al. 2006. Proc Natl Acad Sci U S A. 103: 8822-7. PMID: 16723399
- Non-Hodgkin's lymphomas with Burkitt-like cells are associated with c-Myc amplification and poor prognosis. | Mossafa, H., et al. 2006. Leuk Lymphoma. 47: 1885-93. PMID: 17065002
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
REEP4 Antibody (H-12) | sc-398191 | 200 µg/ml | $322.00 | |||
REEP4 Antibody (H-12): m-IgG Fc BP-HRP Bundle | sc-526295 | 200 µg Ab; 10 µg BP | $361.00 | |||
REEP4 Antibody (H-12): m-IgG2a BP-HRP Bundle | sc-546569 | 200 µg Ab; 10 µg BP | $361.00 | |||
REEP4 Antibody (H-12) AC | sc-398191 AC | 500 µg/ml, 25% agarose | $424.00 | |||
REEP4 Antibody (H-12) HRP | sc-398191 HRP | 200 µg/ml | $322.00 | |||
REEP4 Antibody (H-12) FITC | sc-398191 FITC | 200 µg/ml | $336.00 | |||
REEP4 Antibody (H-12) PE | sc-398191 PE | 200 µg/ml | $349.00 | |||
REEP4 Antibody (H-12) Alexa Fluor® 488 | sc-398191 AF488 | 200 µg/ml | $364.00 | |||
REEP4 Antibody (H-12) Alexa Fluor® 546 | sc-398191 AF546 | 200 µg/ml | $364.00 | |||
REEP4 Antibody (H-12) Alexa Fluor® 594 | sc-398191 AF594 | 200 µg/ml | $364.00 | |||
REEP4 Antibody (H-12) Alexa Fluor® 647 | sc-398191 AF647 | 200 µg/ml | $364.00 | |||
REEP4 Antibody (H-12) Alexa Fluor® 680 | sc-398191 AF680 | 200 µg/ml | $364.00 | |||
REEP4 Antibody (H-12) Alexa Fluor® 790 | sc-398191 AF790 | 200 µg/ml | $364.00 | |||
REEP4 (H-12) Neutralizing Peptide | sc-398191 P | 100 µg/0.5 ml | $69.00 |