RECA-1 Antibody (RECA-1): sc-52665

RECA-1 Antibody (RECA-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects the RECA-1 protein of mouse and rat origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-RECA-1 antibody (RECA-1) is available as a non-conjugated format. RECA-1, also known as rat endothelial cell antigen-1, plays a crucial role in identifying and characterizing endothelial cells, which are essential for maintaining vascular integrity and function. Endothelial cells form a selective barrier that regulates the exchange of substances between the bloodstream and surrounding tissues, thereby influencing processes such as inflammation, blood clotting, and the immune response. RECA-1 expression on the surface of endothelial cells allows for identification of these cells in various tissues, making RECA-1 (RECA-1) antibody a valuable marker in studies related to vascular biology and pathology. Endothelial cells expressing RECA-1 are involved in maintaining vascular homeostasis and play a pivotal role in forming specialized structures like the blood-brain barrier and renal glomerulus, which are critical for organ function and protection. Using RECA-1 (RECA-1) monoclonal antibody in research can provide insights into endothelial cell behavior and their interactions within the vascular system, contributing to a better understanding of cardiovascular diseases and potential therapeutic targets.

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RECA-1 Antibody (RECA-1) References:

1. Blood vessel response to pan-endothelium (RECA-1) antibody in normal and tooth loaded rat periodontal ligament.  |  Sims, MR. 1999. Eur J Orthod. 21: 469-79. PMID: 10565087
2. Expression of Von Willebrand factor, an endothelial cell marker, is up-regulated by angiogenesis factors: a potential method for objective assessment of tumor angiogenesis.  |  Zanetta, L., et al. 2000. Int J Cancer. 85: 281-8. PMID: 10629090
3. Conditionally immortalized retinal capillary endothelial cell lines (TR-iBRB) expressing differentiated endothelial cell functions derived from a transgenic rat.  |  Hosoya, K., et al. 2001. Exp Eye Res. 72: 163-72. PMID: 11161732
4. Labelling of rat endothelial cells with antibodies to vWF, RECA-1, PECAM-1, ICAM-1, OX-43 and ZO-1.  |  Ulger, H., et al. 2002. Anat Histol Embryol. 31: 31-5. PMID: 11841355
5. Circulating thrombomodulin as a novel endothelial cell marker: comparison of its behavior with von Willebrand factor and tissue-type plasminogen activator.  |  Takahashi, H., et al. 1992. Am J Hematol. 41: 32-9. PMID: 1323930
6. Expression of a lymphatic endothelial cell marker in benign and malignant vascular tumors.  |  Xu, H., et al. 2004. Hum Pathol. 35: 857-61. PMID: 15257549
7. Antibodies defining rat endothelial cells: RECA-1, a pan-endothelial cell-specific monoclonal antibody.  |  Duijvestijn, AM., et al. 1992. Lab Invest. 66: 459-66. PMID: 1583886
8. Molecular identification of PAL-E, a widely used endothelial-cell marker.  |  Niemelä, H., et al. 2005. Blood. 106: 3405-9. PMID: 16099878
9. Id1 gene transfer confers angiogenic property on fully differentiated endothelial cells and contributes to therapeutic angiogenesis.  |  Nishiyama, K., et al. 2005. Circulation. 112: 2840-50. PMID: 16267257
10. Improvement of endothelial function by systemic transfusion of vascular progenitor cells.  |  Wassmann, S., et al. 2006. Circ Res. 99: e74-83. PMID: 16990568
11. Characterization and differential expression of an endothelial cell-specific surface antigen in continuous and sinusoidal endothelial, in skin vascular lesions and in vitro.  |  Goerdt, S., et al. 1989. Exp Cell Biol. 57: 185-92. PMID: 2599260
12. Serum angiotensin-converting enzyme: an endothelial cell marker. Application to thromboembolic pathology.  |  Drouet, L., et al. 1988. J Lab Clin Med. 112: 450-7. PMID: 2844937

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-RECA-1 Antibody (RECA-1) has 8 citations in a variety of scientific publications.

Primary antibodies like Anti-RECA-1 Antibody (RECA-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

RECA-1 Antibody (RECA-1) Specifications

Alternate Product Name: RECA-1

Product Clone Name: RECA-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: RECA-1

Epitope Species: rat

Product Reactivity/Detection: RECA-1

Species Reactivity/Detection: mouse, rat

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 8 citations in various scientific publications

Available Conjugates/Forms for RECA-1 Antibody (RECA-1): N/A