RBMX2 Antibody (C-1): sc-518215

RBMX2 Antibody (C-1) is a mouse monoclonal IgM antibody that detects RBMX2 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-RBMX2 antibody (C-1) is available as a non-conjugated monoclonal isotype antibody. RBMX2, or RNA-binding motif protein, X-linked 2, is a 322 amino acid protein belonging to the IST3 family and features a single RNA recognition motif (RRM) domain, which is crucial for RNA processing and regulation. RBMX2 is primarily located in the nucleus, where RBMX2 participates in various RNA-related processes, including splicing and transport, making RBMX2 essential for proper gene expression and cellular function. The RBMX2 gene is intronless and is highly conserved across multiple species, including chimpanzees, dogs, and yeast, indicating fundamental biological importance. RBMX2 maps to the X chromosome at position Xq25, a region associated with several genetic conditions, including Klinefelter′s syndrome and Turner syndrome, which arise from abnormalities in X chromosome number. RBMX2′s ability to interact with other proteins involved in RNA metabolism further underscores significance in maintaining cellular homeostasis and highlights potential as a target for research into X-linked disorders.

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RBMX2 Antibody (C-1) References:

1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.  |  Lai, CH., et al. 2000. Genome Res. 10: 703-13. PMID: 10810093
2. Features of Turner's syndrome in women with polycystic ovaries.  |  Givens, JR., et al. 1975. Obstet Gynecol. 45: 619-24. PMID: 1143721
3. Overall DNA methylation and chromatin structure of normal and abnormal X chromosomes.  |  Bernardino-Sgherri, J., et al. 2002. Cytogenet Genome Res. 99: 85-91. PMID: 12900549
4. The DNA sequence of the human X chromosome.  |  Ross, MT., et al. 2005. Nature. 434: 325-37. PMID: 15772651
5. The molecular basis of variation in human color vision.  |  Deeb, SS. 2005. Clin Genet. 67: 369-77. PMID: 15811001
6. RBMX gene is essential for brain development in zebrafish.  |  Tsend-Ayush, E., et al. 2005. Dev Dyn. 234: 682-8. PMID: 15895365
7. The origin and evolution of human ampliconic gene families and ampliconic structure.  |  Bhowmick, BK., et al. 2007. Genome Res. 17: 441-50. PMID: 17185645
8. Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic.  |  Augui, S., et al. 2007. Science. 318: 1632-6. PMID: 18063799
9. A haplotype at chromosome Xq27.2 confers susceptibility to prostate cancer.  |  Yaspan, BL., et al. 2008. Hum Genet. 123: 379-86. PMID: 18350320
10. Isoform-Level Gene Expression Profiles of Human Y Chromosome Azoospermia Factor Genes and Their X Chromosome Paralogs in the Testicular Tissue of Non-Obstructive Azoospermia Patients.  |  Ahmadi Rastegar, D., et al. 2015. J Proteome Res. 14: 3595-605. PMID: 26162009
11. Global comparison of chromosome X genes of pulmonary telocytes with mesenchymal stem cells, fibroblasts, alveolar type II cells, airway epithelial cells, and lymphocytes.  |  Zhu, Y., et al. 2015. J Transl Med. 13: 318. PMID: 26416664
12. Alu element in the RNA binding motif protein, X-linked 2 (RBMX2) gene found to be linked to bipolar disorder.  |  Laine, P., et al. 2021. PLoS One. 16: e0261170. PMID: 34914762

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-RBMX2 Antibody (C-1) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-RBMX2 Antibody (C-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

RBMX2 Antibody (C-1) Specifications

Alternate Product Name: RBMX2

Product Clone Name: C-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 252-274

Epitope Target: RBMX2

Epitope Species: human

Product Reactivity/Detection: RBMX2

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for RBMX2 Antibody (C-1): N/A