Date published: 2025-11-21

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Ral B Antibody (XY-12): sc-81927

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Datasheets
  • Ral B Antibody (XY-12) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
  • raised against recombinant Ral B of human origin
  • recommended for detection of Ral B of human origin by WB, IP, IF, IHC(P) and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Ral B Antibody (XY-12). This work is in progress.

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    Ral B Antibody (XY-12) is a mouse monoclonal IgG2a antibody that recognizes Ral B in human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Ral B is a member of the Ras-related GTPase family, which plays a crucial role in cellular signaling pathways that regulate biological processes, including cell proliferation, differentiation, and survival. One of the key aspects of Ral B′s function is involvement in phospholipase D (PLD) activation, which is essential for membrane trafficking and cytoskeletal dynamics. This regulation occurs through a Ras/Ral signaling pathway, highlighting Ral B′s importance in cellular communication and response to external stimuli. Additionally, Ral B interacts with specific downstream targets, such as Ral BP-1, which contains a Rho-GTPase-activating domain that preferentially interacts with the Rho family member Cdc42, further emphasizing Ral B′s role in modulating cellular functions. Anti-Ral B antibody (XY-12) serves as an invaluable tool for researchers exploring signaling networks involving Ral B and its implications in human health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Ral B Antibody (XY-12)

    sc-81927
    100 µg/ml
    $333.00

    Can sc-81927: Ral B (XY-12) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: jerojero
    Thank you for your question. Yes, sc-81927: Ral B (XY-12) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-03-24
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    Rated 3 out of 5 by from Acceptable immunoperoxidase membrane andAcceptable immunoperoxidase membrane and cytoplasmic staining in formalin-fixed, paraffin-embedded human colon tissue. -SCBT QC
    Date published: 2015-03-29
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    Ral B Antibody (XY-12) is rated 3.0 out of 5 by 2.
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