Rabies Virus Antibody (6041): sc-58185
- Rabies Virus Antibody (6041) is a mouse monoclonal IgG2a provided at 100 µg/ml
- raised against Rabies virus surface glycoprotein
- recommended for detection of Rabies virus by IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Rabies Virus Antibody (6041). This work is in progress.
QUICK LINKS
SEE ALSO...
Rabies Virus Antibody (6041) is a mouse monoclonal IgG2a antibody that detects Rabies virus with species reactivity specific to Rabies virus by immunofluorescence (IF) applications. Anti-Rabies virus antibody (6041) plays a crucial role in understanding the pathogenesis of rabies, a disease caused by the rabies virus, which is a member of the Rhabdoviridae family. Rabies virus is known for its neurotropic properties, meaning it has a strong affinity for the nervous system, leading to severe central nervous system infections characterized by symptoms such as agitation, paralysis, and ultimately death. Rabies virus′s structure is particularly important; measuring approximately 780 nm in length, and enveloped by a lipid membrane studded with glycoprotein projections. These glycoproteins are essential for Rabies virus′s ability to attach to and enter host cells, facilitating infection. The presence of glycoproteins on Rabies virus′s surface not only aids in infectivity but also serves as a target for immune response, making Rabies virus monoclonal antibody (6041) a valuable tool for researchers studying immune mechanisms against rabies and potential vaccine development. With approximately 50,000 human deaths attributed to rabies each year, accurate detection and study of Rabies virus using Rabies virus (6041) antibody is vital for advancing understanding and control of this deadly disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Rabies Virus Antibody (6041) References:
- Neuronal dysfunction and death in rabies virus infection. | Fu, ZF. and Jackson, AC. 2005. J Neurovirol. 11: 101-6. PMID: 15804968
- Live attenuated rabies virus co-infected with street rabies virus protects animals against rabies. | Wu, X., et al. 2011. Vaccine. 29: 4195-201. PMID: 21514343
- Passive carriage of rabies virus by dendritic cells. | Senba, K., et al. 2013. Springerplus. 2: 419. PMID: 24024103
- Parainfluenza virus 5 expressing the G protein of rabies virus protects mice after rabies virus infection. | Huang, Y., et al. 2015. J Virol. 89: 3427-9. PMID: 25552723
- The ectodomain of rabies virus glycoprotein determines dendritic cell activation. | Huang, J., et al. 2017. Antiviral Res. 141: 1-6. PMID: 28161580
- Integrin β1 Promotes Peripheral Entry by Rabies Virus. | Shuai, L., et al. 2020. J Virol. 94: PMID: 31666383
- Function of Host Protein Staufen1 in Rabies Virus Replication. | Liu, G., et al. 2021. Viruses. 13: PMID: 34452292
- Linking connectome with transcriptome using a self-inactivating rabies virus. | Yao, S. and Levi, BP. 2023. Nat Methods. 20: 493-494. PMID: 36864201
- Rabies virus binding at neuromuscular junctions. | Burrage, TG., et al. 1985. Virus Res. 2: 273-89. PMID: 3890406
- Rabies virus and the problems of rabies vaccination in man. | Crick, J. and Brown, F. 1976. Trans R Soc Trop Med Hyg. 70: 196-201. PMID: 790671
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rabies Virus Antibody (6041) | sc-58185 | 100 µg/ml | $316.00 |