Rab 7 Antibody (D-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects Rab 7 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Rab 7 antibody (D-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Rab 7 is a member of the Ras-related superfamily of guanine nucleotide-binding proteins, which play a crucial role in intracellular transport processes. Specifically, Rab 7 is primarily located on late endosomes and is essential for the transport of cargo from these organelles to lysosomes, thereby facilitating the degradation of cellular waste and recycling of membrane components. Such localization is vital for maintaining cellular homeostasis and regulating the turnover of proteins and lipids, which is particularly important in the context of neurodegenerative diseases where impaired lysosomal function can lead to the accumulation of toxic aggregates. Rab 7′s interaction with various effector proteins further underscores Rab 7′s significance in the endocytic pathway, as Rab 7 orchestrates the fusion of late endosomes with lysosomes, ensuring that cellular debris is efficiently processed and cleared.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rab 7 Antibody (D-4) | sc-271608 | 200 µg/ml | $316.00 | |||
Rab 7 Antibody (D-4): m-IgG Fc BP-HRP Bundle | sc-527265 | 200 µg Ab; 10 µg BP | $354.00 | |||
Rab 7 Antibody (D-4): m-IgG1 BP-HRP Bundle | sc-532638 | 200 µg Ab; 20 µg BP | $354.00 | |||
Rab 7 Antibody (D-4) AC | sc-271608 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Rab 7 Antibody (D-4) HRP | sc-271608 HRP | 200 µg/ml | $316.00 | |||
Rab 7 Antibody (D-4) FITC | sc-271608 FITC | 200 µg/ml | $330.00 | |||
Rab 7 Antibody (D-4) PE | sc-271608 PE | 200 µg/ml | $343.00 | |||
Rab 7 Antibody (D-4) Alexa Fluor® 488 | sc-271608 AF488 | 200 µg/ml | $357.00 | |||
Rab 7 Antibody (D-4) Alexa Fluor® 546 | sc-271608 AF546 | 200 µg/ml | $357.00 | |||
Rab 7 Antibody (D-4) Alexa Fluor® 594 | sc-271608 AF594 | 200 µg/ml | $357.00 | |||
Rab 7 Antibody (D-4) Alexa Fluor® 647 | sc-271608 AF647 | 200 µg/ml | $357.00 | |||
Rab 7 Antibody (D-4) Alexa Fluor® 680 | sc-271608 AF680 | 200 µg/ml | $357.00 | |||
Rab 7 Antibody (D-4) Alexa Fluor® 790 | sc-271608 AF790 | 200 µg/ml | $357.00 | |||
Rab 7 (D-4) Neutralizing Peptide | sc-271608 P | 100 µg/0.5 ml | $68.00 |