Rab 43 Antibody (D-12): sc-515460
- Rab 43 Antibody (D-12) is a mouse monoclonal IgM κ Rab 43 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 39-54 within an internal region of Rab 43 of human origin
- recommended for detection of Rab 43 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Rab 43 Antibody (D-12) for WB applications. This reagent is now offered in a bundle with Rab 43 Antibody (D-12) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Rab 43 Antibody (D-12) is a mouse monoclonal IgM kappa antibody that detects Rab 43 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Rab 43 antibody (D-12) is available as a non-conjugated antibody. Rab 43, also known as ISY1, Rab 41, or Rab 11B, is a crucial member of the Rab family of proteins, which are integral to the processes of endocytosis and biosynthetic protein transport. Rab 43 is primarily localized to the Golgi complex, where Rab 43 plays a vital role in retrograde trafficking to the trans-Golgi network and is essential for the biogenesis and maintenance of Golgi structure. Proper functioning of Rab 43 ensures efficient transport of newly synthesized proteins from the endoplasmic reticulum through the Golgi apparatus to secretory vesicles, thereby facilitating cellular communication and secretion. Additionally, Rab 43 is a target of the GTPase activating protein (GAP) RN-tre, which further underscores Rab 43′s importance in regulating intracellular transport mechanisms. With broad species reactivity and versatile applications, Rab 43 (D-12) antibody is an invaluable tool for researchers studying the dynamics of protein transport and Golgi function in various biological contexts.
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Rab 43 Antibody (D-12) References:
- Isolation, expression pattern of a novel human RAB gene RAB41 and characterization of its intronless homolog RAB41P. | Guo, JH., et al. 2003. DNA Seq. 14: 431-5. PMID: 15018353
- A GTPase-activating protein controls Rab5 function in endocytic trafficking. | Haas, AK., et al. 2005. Nat Cell Biol. 7: 887-93. PMID: 16086013
- Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. | Fuchs, E., et al. 2007. J Cell Biol. 177: 1133-43. PMID: 17562788
- Meeting report: Seventh Annaberg EMBO Workshop 'Membrane traffic in the secretory pathway', Goldegg, Austria, 9-14 January 2007. | Morvan, J., et al. 2007. Traffic. 8: 1111-9. PMID: 17651089
- Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells. | Haas, AK., et al. 2007. J Cell Sci. 120: 2997-3010. PMID: 17684057
- TBC1D20 is a Rab1 GTPase-activating protein that mediates hepatitis C virus replication. | Sklan, EH., et al. 2007. J Biol Chem. 282: 36354-61. PMID: 17901050
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rab 43 Antibody (D-12) | sc-515460 | 200 µg/ml | $322.00 | |||
Rab 43 Antibody (D-12): m-IgGκ BP-HRP Bundle | sc-552734 | 200 µg Ab; 40 µg BP | $361.00 | |||
Rab 43 (D-12) Neutralizing Peptide | sc-515460 P | 100 µg/0.5 ml | $69.00 |