Date published: 2025-10-19

1-800-457-3801

SCBT Portrait Logo
Seach Input

Rab 3A Antibody (9): sc-136050

4.0(2)
Write a reviewAsk a question

Datasheets
  • Rab 3A Antibody (9) is a mouse monoclonal IgG2a, cited in 1 publications, provided at 50 µg/500 µl
  • raised against amino acids 60-220 of Rab 3A of rat origin
  • recommended for detection of Rab 3A of mouse, rat and canine origin by WB, IP and IF; not recommended for IP
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Rab 3A Antibody (9). This work is in progress.

QUICK LINKS

SEE ALSO...

Rab 3A Antibody (9) is a mouse monoclonal IgG2a antibody that detects Rab 3A in mouse, rat, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Rab 3A is a member of the Rab family of small GTPases, which play a crucial role in regulating vesicle trafficking within cells. Rab 3A (9) monoclonal antibody targets a protein predominantly located in neuronal tissues that is essential for the exocytosis of neurotransmitters from synaptic vesicles, making Rab 3A vital for proper synaptic function and communication between neurons. Precise regulation of Rab 3A is critical, as dysregulation can lead to various neurological disorders, highlighting Rab 3A′s importance in maintaining synaptic integrity and neurotransmission. Anti-Rab 3A antibody (9) provides a reliable tool for researchers studying the dynamics of vesicle transport and the underlying mechanisms of synaptic transmission, facilitating advancements in our understanding of neuronal communication and related pathologies.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Rab 3A Antibody (9) References:

  1. Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A.  |  Ostermeier, C. and Brunger, AT. 1999. Cell. 96: 363-74. PMID: 10025402
  2. Rab3a and Rab10 are regulators of lysosome exocytosis and plasma membrane repair.  |  Vieira, OV. 2018. Small GTPases. 9: 349-351. PMID: 27687479
  3. Rab3a-Bound CD63 Is Degraded and Rab3a-Free CD63 Is Incorporated into HIV-1 Particles.  |  Kubo, Y., et al. 2017. Front Microbiol. 8: 1653. PMID: 28900422
  4. O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma.  |  Wu, W., et al. 2018. Cell Death Dis. 9: 970. PMID: 30237463
  5. Small Rab GTPases in Intracellular Vesicle Trafficking: The Case of Rab3A/Raphillin-3A Complex in the Kidney.  |  Martinez-Arroyo, O., et al. 2021. Int J Mol Sci. 22: PMID: 34299299
  6. Rab3A interacts with spastin to regulate neurite outgrowth in hippocampal neurons.  |  Yang, Y., et al. 2023. Biochem Biophys Res Commun. 643: 77-87. PMID: 36587525
  7. Rab3A/Rab27A System Silencing Ameliorates High Glucose-Induced Injury in Podocytes.  |  Martinez-Arroyo, O., et al. 2023. Biology (Basel). 12: PMID: 37237503
  8. Effects of bound nucleotides on the secondary structure, thermal stability, and phosphorylation of Rab3A.  |  Ito, G., et al. 2024. Biochem Biophys Res Commun. 723: 150199. PMID: 38824807
  9. Rab3A small GTP-binding protein in Ca(2+)-dependent exocytosis.  |  Takai, Y., et al. 1996. Genes Cells. 1: 615-32. PMID: 9078389
  10. Rab3A-rabphilin-3A system in neurotransmitter release.  |  Sasaki, T., et al. 1997. Adv Second Messenger Phosphoprotein Res. 31: 279-94. PMID: 9344258

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Rab 3A Antibody (9)

sc-136050
50 µg/500 µl
$316.00

What is the recommended fixation method for immunofluorescence staining with Rab 3A (9): sc-136050 monoclonal antibody?

Asked by: jerojero
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10ºC methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-03-24
  • y_2025, m_10, d_14, h_6CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_136050, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 103ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from Signal via immunofluorescence staining of PCSignal via immunofluorescence staining of PC-12 cells showing cytoplasmic localization. -SCBT QC
Date published: 2015-01-12
Rated 4 out of 5 by from Signal via western blot analysis of Rab 3ASignal via western blot analysis of Rab 3A expression in rat cerebrum tissue extract. -SCBT QC
Date published: 2014-08-04
  • y_2025, m_10, d_14, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_en_US, sid_136050, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 9ms
  • REVIEWS, PRODUCT
Rab 3A Antibody (9) is rated 4.0 out of 5 by 2.
  • y_2025, m_10, d_14, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_en_US, sid_136050, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 102ms
  • REVIEWS, PRODUCT