Rab 38 Antibody (11B-7) is a mouse monoclonal IgG2b antibody that detects Rab 38 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Rab 38 is a crucial member of the Rab family of proteins, specifically localized to the cell membrane, where Rab 38 plays a significant role in melanosomal transport and docking, which is essential for the process of melanogenesis. Rab 38 is particularly important in the transport of melanin-producing proteins, such as TRP1, and proper function is vital for pigmentation in skin, hair, and eyes. Mutations in the gene encoding Rab 38 can lead to oculocutaneous albinism, a genetic condition characterized by a lack of pigment in these tissues, highlighting Rab 38′s critical role in pigmentation and cellular transport mechanisms. Anti-Rab 38 antibody (11B-7) is an invaluable tool for researchers studying the molecular pathways involved in pigmentation and related disorders, providing insights into the underlying mechanisms of melanin production and transport.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rab 38 Antibody (11B-7) | sc-81918 | 100 µg/ml | $333.00 |