QTRTD1 Antibody (B-11): sc-377384
- QTRTD1 Antibody (B-11) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 329-363 within an internal region of QTRTD1 of human origin
- recommended for detection of QTRTD1 of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for QTRTD1 Antibody (B-11). This work is in progress.
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QTRTD1 Antibody (B-11) is a mouse monoclonal IgG2b antibody that detects QTRTD1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). QTRTD1, a 415 amino acid protein, plays a crucial role in tRNA modification and the biosynthesis of queuosine, a modified nucleoside essential for the proper functioning of tRNAs. QTRTD1 is primarily located in the cytoplasm and also associates with the mitochondrial outer membrane, where QTRTD1 forms an active complex with QTRT1, facilitating the exchange of queuine for guanine at the wobble position of tRNAs with GUN anticodons. The significance of this modification lies in its impact on translational fidelity and efficiency, which are vital for protein synthesis and cellular function. QTRTD1 is part of the queuine tRNA-ribosyltransferase family and is encoded by a gene located on human chromosome 3, a region associated with various genetic disorders, including Marfan Syndrome and von Hippel-Lindau syndrome. Anti-QTRTD1 antibody (B-11) is an invaluable tool for researchers studying tRNA modifications and their implications in cellular processes and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
QTRTD1 Antibody (B-11) | sc-377384 | 200 µg/ml | $322.00 | |||
QTRTD1 (B-11) Neutralizing Peptide | sc-377384 P | 100 µg/0.5 ml | $69.00 |