PYK2 Antibody (D-1): sc-365201
- PYK2 Antibody (D-1) is a mouse monoclonal IgA κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-27 at the N-terminus of PYK2 of human origin
- recommended for detection of PYK2 of mouse, rat and human origin by WB, IP, IF and ELISA
- See PYK2 (E-3): sc-393181 for PYK2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for PYK2 Antibody (D-1) for WB applications. This reagent is now offered in a bundle with PYK2 Antibody (D-1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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PYK2 Antibody (D-1) is a mouse monoclonal IgA antibody that detects PYK2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PYK2, also known as proline-rich tyrosine kinase 2, plays a crucial role in cellular signaling, particularly in the central nervous system where PYK2 is highly expressed. PYK2 is involved in the modulation of ion channel function and the activation of the mitogen-activated protein kinase (MAPK) signaling pathway, which are essential for various cellular responses, including growth, differentiation, and survival. PYK2 activation occurs rapidly in response to stimuli that elevate intracellular calcium levels, as well as through the action of phorbol esters that activate protein kinase C (PKC) family members. Notably, PYK2 undergoes significant post-translational modifications, including tyrosine phosphorylation, which are critical for function and regulation. These modifications enhance kinase activity and facilitate interactions with other signaling proteins, thereby amplifying cellular response to external signals. Anti-PYK2 antibody (D-1) is an invaluable tool for researchers studying the intricate signaling pathways mediated by PYK2 and its implications in various physiological and pathological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PYK2 Antibody (D-1) | sc-365201 | 200 µg/ml | $322.00 | |||
PYK2 Antibody (D-1): m-IgGκ BP-HRP Bundle | sc-552007 | 200 µg Ab; 40 µg BP | $361.00 | |||
PYK2 (D-1) Neutralizing Peptide | sc-365201 P | 100 µg/0.5 ml | $69.00 |