PYGB Antibody (B-5): sc-518267
- PYGB Antibody (B-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 716-744 of PYGB of human origin
- recommended for detection of PYGB of human origin by WB, IP, IF and ELISA
- Anti-PYGB Antibody (B-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP is the preferred secondary detection reagent for PYGB Antibody (B-5) for WB applications. This reagent is now offered in a bundle with PYGB Antibody (B-5) (see ordering information below).
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SEE ALSO...
PYGB (B-5) is a mouse monoclonal antibody raised against human PYGB, and detects PYGB in various species, including human, mouse, and rat, by applications such as western blotting (WB), immunohistochemistry, and immunofluorescence (IF). PYGB, or glycogen phosphorylase B, plays a crucial role in glycogen metabolism by catalyzing the breakdown of glycogen into glucose-1-phosphate, which is essential for energy production in cells, particularly during periods of high energy demand. The regulation of PYGB ensures that glucose is available when needed, thus maintaining energy homeostasis in tissues such as muscle and liver. Additionally, PYGB undergoes various post-translational modifications, including phosphorylation, which can influence activity and stability, further underscoring importance in metabolic regulation. PYGB′s interaction with other proteins, such as phosphorylase kinase, highlights a role in complex signaling pathways that govern glycogen mobilization, making PYGB a significant target for research in metabolic disorders and energy-related diseases. Anti-PYGB antibody (B-5) serves as an invaluable tool for researchers investigating the intricate mechanisms of glycogen metabolism and implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PYGB Antibody (B-5) References:
- Comparison of biochemical markers for the detection of minimal myocardial injury: superior sensitivity of cardiac troponin--T ELISA. | Lang, K., et al. 2000. J Intern Med. 247: 119-23. PMID: 10672139
- Glycogen phosphorylase BB in acute coronary syndromes. | Peetz, D., et al. 2005. Clin Chem Lab Med. 43: 1351-8. PMID: 16309372
- Effect of RecF protein on reactions catalyzed by RecA protein. | Madiraju, MV. and Clark, AJ. 1991. Nucleic Acids Res. 19: 6295-300. PMID: 1835535
- rec genes and homologous recombination proteins in Escherichia coli. | Clark, AJ. 1991. Biochimie. 73: 523-32. PMID: 1911953
- Can clonidine, enoximone, and enalaprilat help to protect the myocardium against ischaemia in cardiac surgery? | Boldt, J., et al. 1996. Heart. 76: 207-13. PMID: 8868976
- Glycogen phosphorylase isoenzyme BB in diagnosis of myocardial ischaemic injury and infarction. | Krause, EG., et al. 1996. Mol Cell Biochem. 160-161: 289-95. PMID: 8901485
- Progress in myocardial damage detection: new biochemical markers for clinicians. | Mair, J. 1997. Crit Rev Clin Lab Sci. 34: 1-66. PMID: 9055056
- Glycogen phosphorylase isoenzyme BB to diagnose ischaemic myocardial damage. | Mair, J. 1998. Clin Chim Acta. 272: 79-86. PMID: 9581859
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PYGB Antibody (B-5) | sc-518267 | 200 µg/ml | $322.00 | |||
PYGB Antibody (B-5): m-IgG1 BP-HRP Bundle | sc-551801 | 200 µg Ab; 20 µg BP | $361.00 | |||
PYGB Antibody (B-5) AC | sc-518267 AC | 500 µg/ml, 25% agarose | $424.00 | |||
PYGB Antibody (B-5) HRP | sc-518267 HRP | 200 µg/ml | $322.00 | |||
PYGB Antibody (B-5) FITC | sc-518267 FITC | 200 µg/ml | $336.00 | |||
PYGB Antibody (B-5) PE | sc-518267 PE | 200 µg/ml | $349.00 | |||
PYGB Antibody (B-5) Alexa Fluor® 488 | sc-518267 AF488 | 200 µg/ml | $364.00 | |||
PYGB Antibody (B-5) Alexa Fluor® 546 | sc-518267 AF546 | 200 µg/ml | $364.00 | |||
PYGB Antibody (B-5) Alexa Fluor® 594 | sc-518267 AF594 | 200 µg/ml | $364.00 | |||
PYGB Antibody (B-5) Alexa Fluor® 647 | sc-518267 AF647 | 200 µg/ml | $364.00 | |||
PYGB Antibody (B-5) Alexa Fluor® 680 | sc-518267 AF680 | 200 µg/ml | $364.00 | |||
PYGB Antibody (B-5) Alexa Fluor® 790 | sc-518267 AF790 | 200 µg/ml | $364.00 |