PSMD5 Antibody (35-K): sc-100461
- PSMD5 Antibody (35-K) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against recombinant PSMD5 of human origin
- recommended for detection of PSMD5 of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PSMD5 Antibody (35-K). This work is in progress.
PSMD5 Antibody (35-K) is a mouse monoclonal IgG1 antibody that detects PSMD5 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PSMD5, also known as S5B, is a crucial regulatory component of the 26S proteasome, which plays a vital role in the selective degradation of ubiquitinated proteins, thereby maintaining cellular homeostasis and regulating various cellular processes such as the cell cycle, apoptosis, and stress responses. Located within the 19S regulatory particle of the proteasome, PSMD5 forms a heterotrimeric complex with PSMC1 and PSMC2, facilitating the recognition and unfolding of ubiquitinated substrates. The presence of nine di-leucine repeats and a motif resembling a tyrosine-based motif in PSMD5 suggests involvement in the trafficking and targeting of proteins, which is essential for efficient functioning of the proteasome. Anti-PSMD5 antibody (35-K) enables researchers to gain insights into the dynamics of protein degradation and implications in various diseases, including cancer and neurodegenerative disorders, where proteasome function is often compromised.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSMD5 Antibody (35-K) | sc-100461 | 100 µg/ml | $333.00 |