PSMD4 Antibody (AH1.1): sc-53425

PSMD4 Antibody (AH1.1) is a mouse monoclonal IgG1 antibody that detects PSMD4 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). PSMD4, also known as S5a or the multiubiquitin chain binding protein, plays a crucial role in the selective degradation of cellular proteins, a process vital for maintaining cellular homeostasis and regulating various biological functions. PSMD4 is primarily located in the nucleus and is an essential component of the 26S proteasome, which is responsible for degrading ubiquitinated proteins. Proper functioning of the proteasome ensures that damaged or misfolded proteins are efficiently removed, preventing potential cellular toxicity and contributing to processes such as cell cycle regulation and apoptosis. PSMD4 is expressed in a variety of tissues and may exhibit developmental regulation, with specific isoforms like Rpn10D and Rpn10E potentially playing specialized roles during early embryonic development. Anti-PSMD4 antibody (AH1.1) is an invaluable tool for researchers studying protein degradation pathways and their implications in various diseases, including cancer and neurodegenerative disorders.

The preferred PSMD4 antibody is PSMD4 Antibody (F-6): sc-398033.