Date published: 2025-12-6

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PSMB6 Antibody (JQ-3): sc-100455

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Datasheets
  • PSMB6 Antibody (JQ-3) is a mouse monoclonal IgG2b κ, cited in 3 publications, provided at 100 µg/ml
  • raised against recombinant PSMB6 of human origin
  • recommended for detection of PSMB6 of human origin by WB, IP, IF, IHC(P) and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PSMB6 Antibody (JQ-3). This work is in progress.

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PSMB6 Antibody (JQ-3) is a mouse monoclonal IgG2b antibody that detects PSMB6 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PSMB6, also known as LMPY or proteasome subunit Y, plays a crucial role in the proteolytic function of the 26S Proteasome, which is essential for maintaining cellular homeostasis by selectively degrading ubiquitinated proteins. This process is vital for regulating various cellular functions, including the cell cycle, apoptosis, and the response to oxidative stress. PSMB6 is located within the 20S Proteasome chamber, where PSMB6 contributes to the proteolytic core′s activity, ensuring that damaged or misfolded proteins are efficiently processed and removed from the cell. The structural integrity of PSMB6, along with PSMB6 interaction with other subunits, is critical for the overall functionality of the proteasome, highlighting PSMB6 importance in cellular quality control mechanisms. Anti-PSMB6 antibody (JQ-3) is an invaluable tool for researchers studying proteasome activity and its implications in various diseases, including cancer and neurodegenerative disorders.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

PSMB6 Antibody (JQ-3)

sc-100455
100 µg/ml
$333.00

Can sc-100455: PSMB6 (JQ-3) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: cjMara
Thank you for your question. Yes, sc-100455: PSMB6 (JQ-3) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Great monoclonal antibodyNice strong band observed with PSMB6 Antibody (JQ-3) with little to no background. Immunostain was robust and specific
Date published: 2017-02-09
Rated 5 out of 5 by from Beautiful immunoperoxidase nuclear and cytoplasmicBeautiful immunoperoxidase nuclear and cytoplasmic staining in formalin-fixed, paraffin-embedded human colon tissue. -SCBT QC
Date published: 2015-04-14
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PSMB6 Antibody (JQ-3) is rated 5.0 out of 5 by 3.
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