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PSMB6 Antibody (JQ-3) is a mouse monoclonal IgG2b antibody that detects PSMB6 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PSMB6, also known as LMPY or proteasome subunit Y, plays a crucial role in the proteolytic function of the 26S Proteasome, which is essential for maintaining cellular homeostasis by selectively degrading ubiquitinated proteins. This process is vital for regulating various cellular functions, including the cell cycle, apoptosis, and the response to oxidative stress. PSMB6 is located within the 20S Proteasome chamber, where PSMB6 contributes to the proteolytic core′s activity, ensuring that damaged or misfolded proteins are efficiently processed and removed from the cell. The structural integrity of PSMB6, along with PSMB6 interaction with other subunits, is critical for the overall functionality of the proteasome, highlighting PSMB6 importance in cellular quality control mechanisms. Anti-PSMB6 antibody (JQ-3) is an invaluable tool for researchers studying proteasome activity and its implications in various diseases, including cancer and neurodegenerative disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSMB6 Antibody (JQ-3) | sc-100455 | 100 µg/ml | $333.00 |