PSMB11 Antibody (A-5): sc-514317
- PSMB11 Antibody (A-5) is a mouse monoclonal IgM κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 89-107 within an internal region of PSMB11 of human origin
- recommended for detection of PSMB11 of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PSMB11 Antibody (A-5). This work is in progress.
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PSMB11 Antibody (A-5) is a mouse monoclonal IgM antibody that detects PSMB11 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PSMB11, also known as Proteasome subunit beta type-11 or BETA5T, is a crucial component of the 26S proteasome, a multi-subunit protease complex responsible for the selective degradation of ubiquitinated proteins, which is vital for maintaining cellular homeostasis and regulating various cellular processes. Anti-PSMB11 antibody (A-5) recognizes a protein consisting of 300 amino acids that is particularly important in CD8-positive T-cells, where PSMB11 plays a role in modulating proteasomal activity by reducing chymotrypsin-like activity, thereby influencing the immune response. The structural composition of the 26S proteasome, which includes the 20S proteolytic core and the 19S regulatory particles, underscores the significance of PSMB11 in the proteolytic pathway, as PSMB11 contributes to the precise recognition and unfolding of ubiquitinated substrates, ensuring that only damaged or misfolded proteins are targeted for degradation. PSMB11 monoclonal antibody (A-5) is an essential tool for researchers studying proteasomal function and its implications in various diseases, including cancer and autoimmune disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSMB11 Antibody (A-5) | sc-514317 | 200 µg/ml | $316.00 | |||
PSMB11 (A-5) Neutralizing Peptide | sc-514317 P | 100 µg/0.5 ml | $68.00 |