PSD-95 Antibody (6D677): sc-71933
- PSD-95 Antibody (6D677) is a mouse monoclonal IgG2a κ, cited in 35 publications, provided at 200 µg/ml
- raised against purified recombinant PSD-95 of rat origin
- recommended for detection of PSD-95 of mouse, rat and human origin by WB, IP and IF
- See PSD-95 (7E3): sc-32290 for PSD-95 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for PSD-95 Antibody (6D677) for WB applications. These reagents are now offered in bundles with PSD-95 Antibody (6D677) (see ordering information below).
PSD-95 Antibody (6D677) is a mouse monoclonal IgG2a antibody that detects PSD-95 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). PSD-95, a member of the membrane-associated guanylate kinase (MAGUK) family, plays a crucial role in synaptic signaling and plasticity by organizing and anchoring various proteins at the postsynaptic density of excitatory synapses. This localization is vital for proper synaptic functioning, as PSD-95 facilitates the clustering of receptors and signaling molecules, thereby influencing synaptic strength and communication between neurons. The structural integrity of PSD-95, characterized by PDZ, SH3, and guanylate kinase domains, allows interaction with various proteins, including NMDA and AMPA receptors, which are essential for synaptic transmission and plasticity. By understanding PSD-95′s role in synaptic architecture and function, researchers can gain insights into mechanisms underlying learning, memory, and neurodevelopmental disorders. Anti-PSD-95 antibody (6D677) serves as an invaluable tool for studying these processes and exploring synaptic interactions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSD-95 Antibody (6D677) | sc-71933 | 200 µg/ml | $316.00 | |||
PSD-95 Antibody (6D677): m-IgG Fc BP-HRP Bundle | sc-539425 | 200 µg Ab; 10 µg BP | $354.00 | |||
PSD-95 Antibody (6D677): m-IgG2a BP-HRP Bundle | sc-546703 | 200 µg Ab; 10 µg BP | $354.00 |