PSD-95 Antibody (4E182): sc-71938
- PSD-95 Antibody (4E182) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against purified recombinant PSD-95 of rat origin
- recommended for detection of PSD-95 of mouse, rat and human origin by WB, IP and IF
- See PSD-95 (7E3): sc-32290 for PSD-95 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for PSD-95 Antibody (4E182) for WB applications. This reagent is now offered in a bundle with PSD-95 Antibody (4E182) (see ordering information below).
PSD-95 Antibody (4E182) is a mouse monoclonal IgG2a antibody that detects PSD-95 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). PSD-95, a member of the membrane-associated guanylate kinase (MAGUK) family, plays a crucial role in synaptic signaling and plasticity by organizing and anchoring various proteins at the postsynaptic density of excitatory synapses. PSD-95 is primarily located at the postsynaptic membrane of neurons, where PSD-95 facilitates the clustering of glutamate receptors and other signaling molecules, thereby influencing synaptic strength and communication between neurons. Proper localization of PSD-95 is essential for maintaining synaptic integrity and function, and disruptions in PSD-95 expression or localization have been implicated in various neurological disorders, including schizophrenia and autism spectrum disorders. Anti-PSD-95 antibody (4E182) is an invaluable tool for researchers studying synaptic dynamics and the molecular mechanisms underlying synaptic transmission and plasticity.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSD-95 Antibody (4E182) | sc-71938 | 200 µg/ml | $316.00 | |||
PSD-95 Antibody (4E182): m-IgG Fc BP-HRP Bundle | sc-539430 | 200 µg Ab; 10 µg BP | $354.00 |