PSD-95 Antibody (2Q128): sc-71935
- PSD-95 Antibody (2Q128) is a mouse monoclonal IgG2a κ, cited in 5 publications, provided at 200 µg/ml
- raised against purified recombinant PSD-95 of rat origin
- recommended for detection of PSD-95 of mouse, rat and human origin by WB, IP and IF
- See PSD-95 (7E3): sc-32290 for PSD-95 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for PSD-95 Antibody (2Q128) for WB applications. This reagent is now offered in a bundle with PSD-95 Antibody (2Q128) (see ordering information below).
PSD-95 Antibody (2Q128) is a mouse monoclonal IgG2a antibody that detects PSD-95 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). PSD-95, a member of the membrane-associated guanylate kinase (MAGUK) family, plays a crucial role in synaptic signaling and plasticity by organizing and anchoring various proteins at the postsynaptic density of excitatory synapses. PSD-95 is primarily located at the postsynaptic membrane of neurons, where PSD-95 facilitates the clustering of neurotransmitter receptors and signaling molecules, thereby influencing synaptic strength and communication between neurons. Proper localization of PSD-95 is vital for maintaining synaptic integrity and function, as disruptions in PSD-95 expression or localization can lead to neurodevelopmental disorders and cognitive impairments. Additionally, PSD-95 interacts with several key proteins, including NMDA and AMPA receptors, which are essential for synaptic transmission and plasticity. Anti-PSD-95 antibody (2Q128) enables researchers to gain insights into the dynamics of synaptic organization and the molecular mechanisms underlying various neurological conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSD-95 Antibody (2Q128) | sc-71935 | 200 µg/ml | $322.00 | |||
PSD-95 Antibody (2Q128): m-IgG Fc BP-HRP Bundle | sc-539427 | 200 µg Ab; 10 µg BP | $361.00 |