PRX V Antibody (H-5): sc-133072
- PRX V Antibody (H-5) is a mouse monoclonal IgG1 κ PRX V antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 1-214 representing full length PRX V of human origin
- PRX V Antibody (H-5) is recommended for detection of PRX V of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-PRX V Antibody (H-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PRX V Antibody (H-5). This work is in progress.
PRX V Antibody (H-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects PRX V protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PRX V (H-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PRX V protein, also known as peroxiredoxin-5, plays a crucial role in cellular defense against oxidative stress by reducing reactive oxygen species (ROS) and maintaining redox homeostasis, which is vital for protecting cells from damage and ensuring proper cellular function. PRX V is localized in mitochondria, where PRX V helps to mitigate oxidative damage that can arise from metabolic processes, thereby contributing to mitochondrial health and function. This localization is particularly important as mitochondria are a major source of ROS, and effective antioxidant mechanisms are essential for preventing cellular injury and apoptosis. PRX V is involved in various cellular processes, including cell proliferation and differentiation, highlighting PRX V′s significance in both normal physiology and disease states. PRX V expression is notably high in tissues such as liver, kidney, heart, and lung, and PRX V dysregulation has been implicated in various pathological conditions, including cancer and neurodegenerative diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PRX V Antibody (H-5) References:
- Peroxiredoxin I (macrophage 23 kDa stress protein) is highly and widely expressed in the rat nervous system. | Mizusawa, H., et al. 2000. Neurosci Lett. 283: 57-60. PMID: 10729633
- From cytoprotection to tumor suppression: the multifactorial role of peroxiredoxins. | Butterfield, LH., et al. 1999. Antioxid Redox Signal. 1: 385-402. PMID: 11233141
- Overexpression of peroxiredoxin in human breast cancer. | Noh, DY., et al. 2001. Anticancer Res. 21: 2085-90. PMID: 11497302
- Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimer's disease and Down syndrome. | Kim, SH., et al. 2001. J Neural Transm Suppl. 223-35. PMID: 11771746
- Cell specific expression of peroxiredoxins in human lung and pulmonary sarcoidosis. | Kinnula, VL., et al. 2002. Thorax. 57: 157-64. PMID: 11828047
- Peroxiredoxins. | Hofmann, B., et al. 2002. Biol Chem. 383: 347-64. PMID: 12033427
- Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein. | Fujii, J. and Ikeda, Y. 2002. Redox Rep. 7: 123-30. PMID: 12189041
- Mice with targeted mutation of peroxiredoxin 6 develop normally but are susceptible to oxidative stress. | Wang, X., et al. 2003. J Biol Chem. 278: 25179-90. PMID: 12732627
- Purification, characterization, and cloning of a heme-binding protein (23 kDa) in rat liver cytosol. | Iwahara, S., et al. 1995. Biochemistry. 34: 13398-406. PMID: 7577926
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PRX V Antibody (H-5) | sc-133072 | 200 µg/ml | $316.00 | |||
PRX V Antibody (H-5) AC | sc-133072 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PRX V Antibody (H-5) HRP | sc-133072 HRP | 200 µg/ml | $316.00 | |||
PRX V Antibody (H-5) FITC | sc-133072 FITC | 200 µg/ml | $330.00 | |||
PRX V Antibody (H-5) PE | sc-133072 PE | 200 µg/ml | $343.00 | |||
PRX V Antibody (H-5) Alexa Fluor® 488 | sc-133072 AF488 | 200 µg/ml | $357.00 | |||
PRX V Antibody (H-5) Alexa Fluor® 546 | sc-133072 AF546 | 200 µg/ml | $357.00 | |||
PRX V Antibody (H-5) Alexa Fluor® 594 | sc-133072 AF594 | 200 µg/ml | $357.00 | |||
PRX V Antibody (H-5) Alexa Fluor® 647 | sc-133072 AF647 | 200 µg/ml | $357.00 | |||
PRX V Antibody (H-5) Alexa Fluor® 680 | sc-133072 AF680 | 200 µg/ml | $357.00 | |||
PRX V Antibody (H-5) Alexa Fluor® 790 | sc-133072 AF790 | 200 µg/ml | $357.00 |