PRR19 Antibody (G-1): sc-390446
- PRR19 Antibody (G-1) is a mouse monoclonal IgG1 κ PRR19 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 65-80 within an internal region of PRR19 of human origin
- PRR19 Antibody (G-1) is recommended for detection of PRR19 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine and porcine
- Anti-PRR19 Antibody (G-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for PRR19 Antibody (G-1) for WB and IHC(P) applications. This reagent is now offered in a bundle with PRR19 Antibody (G-1) (see ordering information below).
QUICK LINKS
PRR19 Antibody (G-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects PRR19 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). PRR19 (G-1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PRR19 protein, consisting of 356 amino acids, plays a crucial role in cellular processes, particularly in gene expression regulation and cellular signaling pathways. PRR19 function is vital for maintaining cellular homeostasis and responding to stress, which is important for understanding various diseases, including cancer and neurodegenerative disorders. PRR19 gene is conserved across several species, including chimpanzees, dogs, cows, mice, and rats, and is located on human chromosome 19q13.2, a region known for high gene density and association with several genetic disorders. Chromosome 19 harbors a diverse array of genes, including those linked to immunological functions and traits such as eye and hair color, making PRR19 and its interactions particularly relevant in both basic and clinical research contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PRR19 Antibody (G-1) References:
- A fine physical map of the CACNA1A gene region on 19p13.1-p13.2 chromosome. | Trettel, F., et al. 2000. Gene. 241: 45-50. PMID: 10607897
- Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). | LaPoint, SF., et al. 2000. Adv Anat Pathol. 7: 307-21. PMID: 10976909
- Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters. | Moodie, SJ., et al. 2002. Eur J Immunogenet. 29: 287-91. PMID: 12121272
- Search for the second Peutz-Jeghers syndrome locus: exclusion of the STK13, PRKCG, KLK10, and PSCD2 genes on chromosome 19 and the STK11IP gene on chromosome 2. | Buchet-Poyau, K., et al. 2002. Cytogenet Genome Res. 97: 171-8. PMID: 12438709
- The DNA sequence and biology of human chromosome 19. | Grimwood, J., et al. 2004. Nature. 428: 529-35. PMID: 15057824
- Immunogenetics of killer cell immunoglobulin-like receptors. | Parham, P. 2005. Mol Immunol. 42: 459-62. PMID: 15607799
- BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription. | Brocke-Heidrich, K., et al. 2006. Oncogene. 25: 7297-304. PMID: 16732314
- A novel CADASIL-causing mutation in a stroke patient. | Vikelis, M., et al. 2007. Swiss Med Wkly. 137: 323-5. PMID: 17629811
- Proline-Rich Protein Tyrosine Kinase 2 in Inflammation and Cancer. | Zhu, X., et al. 2018. Cancers (Basel). 10: PMID: 29738483
- Chromosomal localization of the carcinoembryonic antigen gene family and differential expression in various tumors. | Zimmermann, W., et al. 1988. Cancer Res. 48: 2550-4. PMID: 3356015
- PDE4 inhibition by difamilast regulates filaggrin and loricrin expression via keratinocyte proline-rich protein in human keratinocytes. | Tsuji, G., et al. 2023. J Dermatol Sci. 110: 61-68. PMID: 37156706
- Keratinocyte proline-rich protein modulates immune and epidermal response in imiquimod-induced psoriatic skin inflammation. | Matsuno, A., et al. 2023. Exp Dermatol. 32: 2121-2130. PMID: 37926955
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PRR19 Antibody (G-1) | sc-390446 | 200 µg/ml | $316.00 | |||
PRR19 Antibody (G-1): m-IgG Fc BP-HRP Bundle | sc-526160 | 200 µg Ab; 10 µg BP | $354.00 | |||
PRR19 Antibody (G-1) AC | sc-390446 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PRR19 Antibody (G-1) HRP | sc-390446 HRP | 200 µg/ml | $316.00 | |||
PRR19 Antibody (G-1) FITC | sc-390446 FITC | 200 µg/ml | $330.00 | |||
PRR19 Antibody (G-1) PE | sc-390446 PE | 200 µg/ml | $343.00 | |||
PRR19 Antibody (G-1) Alexa Fluor® 488 | sc-390446 AF488 | 200 µg/ml | $357.00 | |||
PRR19 Antibody (G-1) Alexa Fluor® 546 | sc-390446 AF546 | 200 µg/ml | $357.00 | |||
PRR19 Antibody (G-1) Alexa Fluor® 594 | sc-390446 AF594 | 200 µg/ml | $357.00 | |||
PRR19 Antibody (G-1) Alexa Fluor® 647 | sc-390446 AF647 | 200 µg/ml | $357.00 | |||
PRR19 Antibody (G-1) Alexa Fluor® 680 | sc-390446 AF680 | 200 µg/ml | $357.00 | |||
PRR19 Antibody (G-1) Alexa Fluor® 790 | sc-390446 AF790 | 200 µg/ml | $357.00 | |||
PRR19 (G-1) Neutralizing Peptide | sc-390446 P | 100 µg/0.5 ml | $68.00 |