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PRPS2 Antibody (4C11) is a mouse monoclonal IgG2a light chain antibody that detects phosphoribosyl pyrophosphate synthetase 2 (PRPS2) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). PRPS2 plays a crucial role in nucleotide biosynthesis by catalyzing the synthesis of phosphoribosyl pyrophosphate (PRPP), a key substrate in the production of nearly all nucleotides, which are essential for DNA and RNA synthesis. The importance of PRPS2 is underscored by involvement in purine metabolism, as PRPS2 helps regulate the availability of nucleotides necessary for cellular functions, including energy transfer and signaling. Structurally, PRPS2 is a 318 amino acid protein that can form both homodimers and hexamers, with the hexamer being composed of three homodimers. This unique structural arrangement is significant because PRPS2 may influence enzyme activity and stability, thereby impacting the overall efficiency of nucleotide synthesis in various physiological contexts. Anti-PRPS2 antibody (4C11) is an invaluable tool for researchers studying nucleotide metabolism and its implications in cellular processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PRPS2 Antibody (4C11) | sc-134425 | 100 µg/ml | $339.00 |