PRP19 Antibody (36-K): sc-101236
- PRP19 Antibody (36-K) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against recombinant PRP19 of human origin
- recommended for detection of PRP19 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PRP19 Antibody (36-K). This work is in progress.
PRP19 Antibody (36-K) is a mouse monoclonal IgG2a light chain antibody that detects PRP19 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). PRP19 plays a crucial role in the spliceosome, a complex responsible for pre-mRNA splicing, which is essential for the proper expression of genes in eukaryotic cells. PRP19 is part of the PRP19-associated complex, which is vital for the stable association of U5 and U6 snRNPs with the spliceosome after the release of U4. PRP19′s interaction with the spliceosome not only facilitates the remodeling of the U6/5′ splice site interaction but also leads to the destabilization of Lsm proteins, allowing U6 to engage more effectively with the intron sequence. Understanding PRP19′s function is important because any dysregulation in splicing can lead to various diseases, including cancer and neurodegenerative disorders. Anti-PRP19 antibody (36-K) is an invaluable tool for researchers studying the intricacies of RNA processing and its implications in cellular function and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PRP19 Antibody (36-K) | sc-101236 | 100 µg/ml | $333.00 |