PRORP Antibody (D-2): sc-390380
- PRORP Antibody (D-2) is a mouse monoclonal IgG2a κ PRORP antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 545-579 near the C-terminus of PRORP of human origin
- PRORP Antibody (D-2) is recommended for detection of PRORP of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-PRORP Antibody (D-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PRORP Antibody (D-2) for WB applications. These reagents are now offered in bundles with PRORP Antibody (D-2) (see ordering information below).
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PRORP Antibody (D-2) is a mouse monoclonal IgG2a kappa light chain antibody that detects PRORP protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PRORP (D-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. PRORP protein plays a crucial role in RNA processing, specifically in the maturation of precursor ribonucleic acids, which is essential for proper functioning of cellular processes. This function ensures the production of functional ribonucleoproteins, which are vital for protein synthesis and gene expression regulation. Disruptions in PRORP activity can lead to various cellular dysfunctions, highlighting its significance in maintaining cellular homeostasis. Chromosome 14, where the PRORP gene is located, harbors several other critical genes, including those associated with genetic disorders and diseases, further underscoring the importance of studying PRORP in the context of health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PRORP Antibody (D-2) References:
- The DNA sequence and analysis of human chromosome 14. | Heilig, R., et al. 2003. Nature. 421: 601-7. PMID: 12508121
- A presenilin 1 R278I mutation presenting with language impairment. | Godbolt, AK., et al. 2004. Neurology. 63: 1702-4. PMID: 15534260
- Pathological and physiological functions of presenilins. | Vetrivel, KS., et al. 2006. Mol Neurodegener. 1: 4. PMID: 16930451
- Presenilin-1 mutation E318G and familial Alzheimer's disease in the Italian population. | Albani, D., et al. 2007. Neurobiol Aging. 28: 1682-8. PMID: 16952411
- Molecular cytogenetic characterization of t(14;19)(q32;p13), a new recurrent translocation in B cell malignancies. | Micci, F., et al. 2007. Virchows Arch. 450: 559-65. PMID: 17406891
- The promise of gene therapy for the treatment of alpha-1 antitrypsin deficiency. | Cruz, PE., et al. 2007. Pharmacogenomics. 8: 1191-8. PMID: 17924834
- Alpha1-antitrypsin deficiency: current perspective on research, diagnosis, and management. | Stolk, J., et al. 2006. Int J Chron Obstruct Pulmon Dis. 1: 151-60. PMID: 18046892
- RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme. | Holzmann, J., et al. 2008. Cell. 135: 462-74. PMID: 18984158
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. | Nagase, T., et al. 1997. DNA Res. 4: 141-50. PMID: 9205841
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PRORP Antibody (D-2) | sc-390380 | 200 µg/ml | $316.00 | |||
PRORP Antibody (D-2): m-IgGκ BP-HRP Bundle | sc-523512 | 200 µg Ab, 40 µg BP | $354.00 | |||
PRORP Antibody (D-2): m-IgG2a BP-HRP Bundle | sc-546162 | 200 µg Ab; 10 µg BP | $354.00 | |||
PRORP Antibody (D-2) AC | sc-390380 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PRORP Antibody (D-2) HRP | sc-390380 HRP | 200 µg/ml | $316.00 | |||
PRORP Antibody (D-2) FITC | sc-390380 FITC | 200 µg/ml | $330.00 | |||
PRORP Antibody (D-2) PE | sc-390380 PE | 200 µg/ml | $343.00 | |||
PRORP Antibody (D-2) Alexa Fluor® 488 | sc-390380 AF488 | 200 µg/ml | $357.00 | |||
PRORP Antibody (D-2) Alexa Fluor® 546 | sc-390380 AF546 | 200 µg/ml | $357.00 | |||
PRORP Antibody (D-2) Alexa Fluor® 594 | sc-390380 AF594 | 200 µg/ml | $357.00 | |||
PRORP Antibody (D-2) Alexa Fluor® 647 | sc-390380 AF647 | 200 µg/ml | $357.00 | |||
PRORP Antibody (D-2) Alexa Fluor® 680 | sc-390380 AF680 | 200 µg/ml | $357.00 | |||
PRORP Antibody (D-2) Alexa Fluor® 790 | sc-390380 AF790 | 200 µg/ml | $357.00 | |||
PRORP (D-2) Neutralizing Peptide | sc-390380 P | 100 µg/0.5 ml | $68.00 |