Primaquine phosphate (CAS 63-45-6)
QUICK LINKS
Primaquine phosphate is extensively used in biochemical research to investigate the mechanisms of oxidative stress in cells. Its active metabolite is of particular interest in studies focusing on the generation of reactive oxygen species and their effects on cellular structures, such as membranes and DNA. In molecular biology, Primaquine phosphate serves as a tool to understand the response of various cell types to oxidative damage and the role of detoxifying enzymes in protecting cell integrity. Additionally, researchers utilize Primaquine phosphate to explore the dynamics of red blood cell metabolism, given its selective activity within these cells. In the field of toxicology, the compound is studied to assess the biochemical basis of its species-specific and dose-dependent effects, which are for understanding its safety profile and environmental impact.
Primaquine phosphate (CAS 63-45-6) References
- Inhibition of cardiac Na+ current by primaquine. | Orta-Salazar, G., et al. 2002. Br J Pharmacol. 135: 751-63. PMID: 11834623
- Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targeting. | Bhadra, D., et al. 2005. Int J Pharm. 295: 221-33. PMID: 15848007
- Development and validation of UPLC method for determination of primaquine phosphate and its impurities. | Dongre, VG., et al. 2008. J Pharm Biomed Anal. 46: 236-42. PMID: 18029132
- Formulation and evaluation of taste masked oral reconstitutable suspension of primaquine phosphate. | Shah, PP. and Mashru, RC. 2008. AAPS PharmSciTech. 9: 1025-30. PMID: 18770047
- Biowaiver monographs for immediate-release solid oral dosage forms: primaquine phosphate. | Nair, A., et al. 2012. J Pharm Sci. 101: 936-45. PMID: 22161739
- Toxicological study of the primaquine phosphate loaded chitosan nanoparticles in mice. | Rajera, R., et al. 2013. Int J Biol Macromol. 62: 18-24. PMID: 23973494
- Receptor-mediated hepatocyte-targeted delivery of primaquine phosphate nanocarboplex using a carbohydrate ligand. | Joshi, VM. and Devarajan, PV. 2014. Drug Deliv Transl Res. 4: 353-64. PMID: 25787067
- Design, characterization and antimalarial efficacy of PEGylated galactosylated nano lipid carriers of primaquine phosphate. | Baruah, UK., et al. 2018. Artif Cells Nanomed Biotechnol. 46: 1809-1829. PMID: 29087218
- Primaquine phosphate induces the apoptosis of ATRA-resistant acute promyelocytic leukemia cells by inhibition of the NF-κB pathway. | Ma, L., et al. 2020. J Leukoc Biol. 107: 685-693. PMID: 32125014
- PHARMACOKINETICS OF PRIMAQUINE PHOSPHATE AFTER A SINGLE ORAL ADMINISTRATION TO AFRICAN PENGUINS (SPHENISCUS DEMERSUS). | Carag, JH., et al. 2021. J Zoo Wildl Med. 52: 75-80. PMID: 33827163
- Simultaneous spectrophotometric determination of amodiaquine-primaquine mixtures in dosage forms. | Hassan, SM., et al. 1983. J Assoc Off Anal Chem. 66: 1433-5. PMID: 6643353
- Spectrophotometric determination of primaquine phosphate in pharmaceutical preparations. | Abou Ouf, AA., et al. 1980. Analyst. 105: 1113-8. PMID: 7457893
- Comparative mutagenic and genotoxic effects of three antimalarial drugs, chloroquine, primaquine and amodiaquine. | Chatterjee, T., et al. 1998. Mutagenesis. 13: 619-24. PMID: 9862194
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Primaquine phosphate, 5 g | sc-205817 | 5 g | $82.00 | |||
Primaquine phosphate, 10 g | sc-205817A | 10 g | $174.00 |