PPIL2 Antibody (D-8): sc-398200
- PPIL2 Antibody (D-8) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 346-369 within an internal region of PPIL2 of human origin
- recommended for detection of PPIL2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and porcine
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PPIL2 Antibody (D-8) for WB applications. These reagents are now offered in bundles with PPIL2 Antibody (D-8) (see ordering information below).
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PPIL2 Antibody (D-8) is a mouse monoclonal IgG2b antibody that detects PPIL2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PPIL2, also known as cyclophilin-60 or Cyp60, is a 520 amino acid nuclear protein that plays a crucial role in protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds, a process essential for proper protein conformation and function. PPIL2 is highly expressed in tissues such as testis, pancreas, and placenta, and appears in various cancers, including melanomas and lymphomas, suggesting involvement in tumorigenesis and cellular stress responses. PPIL2′s presence in these tissues highlights importance in cellular processes, including cell proliferation and differentiation. Additionally, PPIL2 exists in two alternatively spliced isoforms, contributing to diverse functional roles in different cellular contexts. The gene encoding PPIL2 is located on human chromosome 22q11.21, emphasizing significance in human health and disease. With broad species reactivity and versatile applications, anti-PPIL2 antibody (D-8) serves as an invaluable tool for studying protein folding mechanisms and biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PPIL2 Antibody (D-8) | sc-398200 | 200 µg/ml | $322.00 | |||
PPIL2 Antibody (D-8): m-IgGκ BP-HRP Bundle | sc-535998 | 200 µg Ab; 40 µg BP | $361.00 | |||
PPIL2 Antibody (D-8): m-IgG2b BP-HRP Bundle | sc-549502 | 200 µg Ab; 10 µg BP | $361.00 | |||
PPIL2 (D-8) Neutralizing Peptide | sc-398200 P | 100 µg/0.5 ml | $69.00 |