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PPARγ Antibody (E-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects PPARγ protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PPARγ (E-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, phycoerythrin, fluorescein isothiocyanate, and multiple Alexa Fluor® conjugates. PPARγ monoclonal antibody (E-8) is recommended for detecting both PPARγ1 and PPARγ2 gene products. PPARγ, a member of the nuclear hormone receptor superfamily, plays a crucial role in regulating gene expression related to insulin sensitivity, adipocyte differentiation, and lipid metabolism. Formation of heterodimers with retinoid X receptors (RXRs) allows modulation of gene transcription involved in critical metabolic processes, influencing pathophysiology of conditions such as obesity, diabetes, and cardiovascular diseases. PPARγ regulates inflammation and influences macrophage activity, which is vital for maintaining immune homeostasis. PPARγ mouse monoclonal antibody (E-8) supports research studying implications in metabolic disorders and interactions with various ligands, including prostanoids and thiazolidinediones, which can activate transcriptional activity. Pro12Ala polymorphism in PPARγ2 gene has been associated with altered transactivation capabilities and may impact immune response to oxidized low-density lipoprotein, linking to type 2 diabetes and abdominal obesity.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PPARγ Antibody (E-8) | sc-7273 | 200 µg/ml | $316.00 | |||
PPARγ Antibody (E-8): m-IgG Fc BP-HRP Bundle | sc-526493 | 200 µg Ab; 10 µg BP | $354.00 | |||
PPARγ Antibody (E-8): m-IgG1 BP-HRP Bundle | sc-531866 | 200 µg Ab; 20 µg BP | $354.00 | |||
PPARγ Antibody (E-8) X | sc-7273 X | 200 µg/0.1 ml | $316.00 | |||
PPARγ Antibody (E-8) AC | sc-7273 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PPARγ Antibody (E-8) FITC | sc-7273 FITC | 200 µg/ml | $330.00 | |||
PPARγ Antibody (E-8) PE | sc-7273 PE | 200 µg/ml | $343.00 | |||
PPARγ Antibody (E-8) Alexa Fluor® 488 | sc-7273 AF488 | 200 µg/ml | $357.00 | |||
PPARγ Antibody (E-8) Alexa Fluor® 546 | sc-7273 AF546 | 200 µg/ml | $357.00 | |||
PPARγ Antibody (E-8) Alexa Fluor® 594 | sc-7273 AF594 | 200 µg/ml | $357.00 | |||
PPARγ Antibody (E-8) Alexa Fluor® 647 | sc-7273 AF647 | 200 µg/ml | $357.00 | |||
PPARγ Antibody (E-8) Alexa Fluor® 680 | sc-7273 AF680 | 200 µg/ml | $357.00 | |||
PPARγ Antibody (E-8) Alexa Fluor® 790 | sc-7273 AF790 | 200 µg/ml | $357.00 | |||
PPARγ Antibody (E-8) B | sc-7273 B | 200 µg/ml | $320.00 | |||
PPARγ Antibody (E-8) TRITC | sc-7273 TRITC | 200 µg/ml | $320.00 | |||
PPARγ Antibody (E-8) Alexa Fluor® 405 | sc-7273 AF405 | 200 µg/ml | $357.00 | |||
Anti-PPARγ (E-8) Blocking Peptide | sc-7273 P | 100 µg/0.5 ml | $68.00 |