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PP2B-B2 Antibody (MH-94) is a mouse monoclonal IgG2a antibody that detects PP2B-B2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). PP2B-B2, also known as PPP3R2, is a 170 amino acid protein that plays a crucial role as a regulatory subunit of calcineurin, a calcium-dependent protein phosphatase essential for various cellular processes, including T-cell activation and neuronal signaling. PP2B-B2 is characterized by four EF-hand domains, which are critical for calcium binding and influence activity and interaction with other proteins. PP2B-B2 exhibits testis-specific expression, suggesting a specialized function in reproductive biology. PP2B-B2 is encoded by a gene located on human chromosome 9q31.1 and is highly conserved across species, indicating a fundamental role in cellular signaling pathways. PP2B-B2′s ability to interact with other proteins, such as calmodulin, further underscores its importance in mediating calcium signaling and regulating various physiological responses. Anti-PP2B-B2 antibody (MH-94) is an invaluable tool for researchers studying the intricate mechanisms of protein phosphatases and their impact on cellular functions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PP2B-B2 Antibody (MH-94) | sc-134423 | 100 µg/ml | $333.00 |