PP2A-Cα/β Antibody (G-4): sc-166034
- PP2A-Cα/β Antibody (G-4) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 275-309 at the C-terminus of PP2A-Cα/β of human origin
- recommended for detection of PP2A-Cα/β of mouse, rat, human and origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- See PP2A-Cα/β (1D6): sc-80665 for PP2A-Cα/β antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PP2A-Cα/β Antibody (G-4) for WB and IHC(P) applications. These reagents are now offered in bundles with PP2A-Cα/β Antibody (G-4) (see ordering information below).
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PP2A-Cα/β Antibody (G-4) is a mouse monoclonal IgG1 antibody that detects PP2A-Cα/β in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PP2A-Cα/β is a critical component of the protein phosphatase 2A (PP2A) family, which plays a vital role in cellular signaling by dephosphorylating serine and threonine residues on target proteins, thereby regulating numerous cellular processes such as cell division, apoptosis, and metabolic homeostasis. The structure of PP2A-Cα/β forms a trimeric complex with a regulatory subunit and a variable subunit, which is essential for enzymatic activity and specificity. This structural arrangement allows PP2A to interact with a diverse array of regulatory subunits, enabling modulation of various signaling pathways effectively. The ability to form different holoenzyme complexes determines substrate specificity and cellular localization, ultimately influencing key biological processes. Anti-PP2A-Cα/β antibody (G-4) serves as an invaluable tool for researchers studying the intricate roles of protein phosphatases in health and disease, providing insights into regulatory mechanisms and potential therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PP2A-Cα/β Antibody (G-4) | sc-166034 | 200 µg/ml | $322.00 | |||
PP2A-Cα/β Antibody (G-4): m-IgGκ BP-HRP Bundle | sc-534694 | 200 µg Ab; 40 µg BP | $361.00 | |||
PP2A-Cα/β Antibody (G-4): m-IgG1 BP-HRP Bundle | sc-538873 | 200 µg Ab; 20 µg BP | $361.00 | |||
PP2A-Cα/β (G-4) Neutralizing Peptide | sc-166034 P | 100 µg/0.5 ml | $69.00 |