Poliovirus Type 3 Antibody (HYB 300-05): sc-80562
- Poliovirus Type 3 Antibody (HYB 300-05) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against inactivated Poliovirus Type 3
- recommended for detection of Poliovirus Type 3 by ELISA; non cross-reactive with Poliovirus Type 1 or Type 2
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Poliovirus Type 3 Antibody (HYB 300-05). This work is in progress.
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Poliovirus Type 3 Antibody (HYB 300-05) is a mouse monoclonal IgG2a antibody that detects Poliovirus by enzyme-linked immunosorbent assay (ELISA). Poliovirus is a small RNA virus belonging to the Picornaviridae family, and anti-Poliovirus antibody (HYB 300-05) helps understand its structure, which consists of a single-stranded RNA genome encapsulated in a protein shell known as a capsid. The capsid is composed of 60 copies each of four structural proteins (VP1, VP2, VP3, and VP4), which play a vital role in the virus′s ability to infect host cells. The structural integrity of the capsid is essential for the virus′s stability and capacity to evade the host immune response, making Poliovirus (HYB 300-05) monoclonal antibody a key tool for vaccine development and therapeutic interventions. Poliovirus Type 3 (HYB 300-05) antibody is instrumental in research focused on understanding viral biology and developing strategies to combat poliomyelitis, a disease that can lead to severe neurological complications.
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Poliovirus Type 3 Antibody (HYB 300-05) References:
- A method to detect low levels of enteric viruses in contaminated oysters. | Shieh, YC., et al. 1999. Appl Environ Microbiol. 65: 4709-14. PMID: 10543775
- Antigenic sites of poliovirus type 3 eliciting IgA monoclonal antibodies in orally immunized mice. | Buttinelli, G., et al. 2001. Virology. 281: 265-71. PMID: 11277698
- Outbreak of poliomyelitis due to type 3 poliovirus, northern India, 1999-2000: injections a major contributing factor. | Kohler, KA., et al. 2003. Int J Epidemiol. 32: 272-7. PMID: 12714548
- Molecular mechanisms of attenuation of the Sabin strain of poliovirus type 3. | Guest, S., et al. 2004. J Virol. 78: 11097-107. PMID: 15452230
- Evidence for a causal association between oral polio vaccine and transverse myelitis: A case history and review of the Literature. | Kelly, H. 2006. J Paediatr Child Health. 42: 155-9. PMID: 16630313
- Intratypic differentiation of poliovirus strains by enzyme-linked immunosorbent assay (ELISA): poliovirus type 2 and poliovirus type 3. | Glikmann, G., et al. 1987. J Virol Methods. 18: 25-36. PMID: 2826518
- Risk Assessment and Virological Monitoring Following an Accidental Exposure to Concentrated Sabin Poliovirus Type 3 in France, November 2018. | Jeannoël, M., et al. 2020. Vaccines (Basel). 8: PMID: 32580378
- Poliovirus type 3: molecular cloning of the genome and nucleotide sequence of the region encoding the protease and polymerase proteins. | Cann, AJ., et al. 1983. Nucleic Acids Res. 11: 1267-81. PMID: 6298739
- The nucleotide sequence of poliovirus type 3 leon 12 a1b: comparison with poliovirus type 1. | Stanway, G., et al. 1983. Nucleic Acids Res. 11: 5629-43. PMID: 6310508
- Poliovirus type 3/Saukett: antigenic and structural correlates of sequence variation in the capsid proteins. | Huovilainen, A., et al. 1994. Virology. 199: 228-32. PMID: 8116248
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Poliovirus Type 3 Antibody (HYB 300-05) | sc-80562 | 100 µg/ml | $316.00 |