Poliovirus Type 3 Inhibitors

The chemical class of Poliovirus Type 3 Inhibitors encompasses a variety of compounds that can potentially disrupt different stages of the Poliovirus Type 3 life cycle. This class includes antiviral agents like Pleconaril, which specifically target the viral capsid proteins, preventing uncoating and replication. Guanidine Hydrochloride and 2'-C-Methylcytidine are known to interfere with viral RNA replication processes, thus hindering the synthesis of viral genetic material.

Ribavirin, a broad-spectrum antiviral, has mechanisms that include the inhibition of RNA-dependent RNA polymerase, making it potentially effective against RNA viruses like Poliovirus Type 3. Enviroxime and Rupintrivir (AG7088) target specific proteins involved in viral RNA replication, further demonstrating the diversity of potential inhibition mechanisms. Chloroquine, although primarily an antimalarial drug, exhibits broad antiviral properties that might disrupt the required pH conditions for viral replication or entry.